Evidence map›Paper›PMID 40779239›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2026

Role of prehabilitative gastrostomy tube feeding to bridge severely malnourished surgically unfit achalasia patients to per-oral endoscopic myotomy.

Biswa Ranjan Patra, Chetan Saner, Shubham Gupta, Yash Harwani, Sidharth Harindranath, Nitish Patwardhan, Yash Kallurwar, Ankita Singh, Arun Vaidya, Prajakta Mane and 2 more

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Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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12 authors.

Biswa Ranjan PatraDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Chetan SanerDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Shubham GuptaDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Yash HarwaniDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Sidharth HarindranathDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Nitish PatwardhanDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Yash KallurwarDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Ankita SinghDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Arun VaidyaDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Prajakta ManeDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Megha MeshramDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India.
Akash ShuklaDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, 400 012, India. drakashshukla@yahoo.com.ORCID http://orcid.org/0000-0001-7718-9452

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimAchalasia cardia may be associated with a risk of severe malnutrition, causing unique challenges in nutritional and definitive management. This study aims to evaluate a novel nutrition strategy in severely malnourished, surgically unfit patients, using percutaneous endoscopic gastrostomy (PEG) tube feeding to improve nutrition followed by per-oral endoscopic myotomy (POEM).

methodsWe conducted a prospective study of achalasia cardia patients from September 2023 to September 2024 at a tertiary care centre. Patients with severe malnutrition (body mass index [BMI] < 16.0 kg/m

resultsAmong 45 achalasia patients, eight (17.77%) met the inclusion criteria. The median Eckardt score was 10 (range 9-11), with a median symptom duration of 3.5 years (range 2-10). Six patients had type-I and two had type- II achalasia, including two with prior treatment failures. Two patients died even before PEG placement due to severe infections at presentation. The remaining six patients underwent PEG feeding, gaining an average of 11.96 (± 2.68) kg over 11.33 (± 0.94) weeks. This was associated with significant improvement in BMI (13.9 to 19.15; p < 0.00001), albumin (2.8 to 4.2; p < 0.0001), mid-arm circumference (17.27 vs. 22.64; p < 0.001), biceps skin fold thickness (2.15 vs. 3.61; p < 0.001) and triceps skin fold thickness (3.25 vs. 5.84; p < 0.001). All patients then successfully underwent POEM, achieving 100% technical and clinical success.

conclusionPatients with severe malnutrition (based on BMI and serum albumin) with achalasia considered unfit for POEM or surgery can be managed safely and effectively by using PEG tube feeding as bridge to successful POEM treatment.

Indexed as

Enteral NutritionEsophageal AchalasiaGastrostomyMalnutritionMyotomyPreoperative CarePyloromyotomyAdultAgedBody Mass IndexFemaleHumansMaleMiddle AgedNutritional StatusProspective StudiesAchalasia cardiaPercutaneous endoscopic gastrostomy (PEG) feedingPer-oral endoscopic myotomyPrehabilitative gastrostomy tube feedingSevere malnutritionSurgically unfit

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.