ArticleDiscover oncology2025
Eosinophilic solid and cystic renal cell carcinoma: a case study of the youngest surgical patient.
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Eosinophilic solid and cystic renal cell carcinoma: a case report of a young Ghanaian female.Journal of surgical case reports · 2026Article
- Case Report: Clinical pathological characteristics, diagnosis, and treatment analysis of eosinophilic solid and cystic renal cell carcinoma: experience from a five-case series.Frontiers in oncology · 2025Article
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11 authors.
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Abstract
backgroundEosinophilic solid and cystic renal cell carcinoma (ESC RCC) is a rare subtype of renal cell carcinoma. The tumor often presents without specific clinical symptoms or detectable signs for a definitive diagnosis. The vast majority of ESC RCC are sporadic, with a few associated with tuberous sclerosis. This case report details a young patient diagnosed with ESC RCC. We recommend complete excision of the tumor after a comprehensive evaluation, followed by postoperative pathology, to achieve a conclusive diagnosis. An 8-year-old boy was incidentally found to have multifocal renal masses in the right kidney during routine physical examination one year ago, without presenting abdominal pain or hematuria. Contrast-enhanced abdominal computed tomography (CT) revealed two isodense masses (27 × 21 mm and 20 × 16 mm) at the upper pole of the right kidney. PET imaging showed no signs of metastasis. The patient underwent robot-assisted partial nephrectomy, and postoperative pathological examination diagnosed ESC RCC. Genetic testing showed no significant abnormalities. After 8 months of follow-up, there were no signs of recurrence or metastasis. This ESC RCC case is likely the youngest case reported to date in urological oncology records, according to current data.
conclusionA combination of imaging studies and postoperative pathological examination is crucial for the definitive diagnosis of rare tumors. For small renal tumors with well-defined borders, no evidence of metastasis, and no tumor thrombus, robot-assisted laparoscopic partial nephrectomy is a viable treatment option for pediatric renal tumors. The pathogenesis of ESC RCC requires further investigation with more data.
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