Evidence map›Paper›PMID 40779137›Full record

ArticleIrish journal of medical science2025

Radiation Dose Estimation and Lifetime Attributable Risk of Radiation-Induced Cancer from Chest CT in COVID-19 Patients.

Husam H Mansour, Noor Khairiah A Karim, Noor Diyana Osman, Rohayu Hami, Yasser S Alajerami

Abstract read
In one paragraph

Article in Irish journal of medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Husam H MansourDepartment of Biomedical Imaging, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Pulau Pinang, Malaysia.
Noor Khairiah A KarimDepartment of Biomedical Imaging, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Pulau Pinang, Malaysia. drkhairiah@usm.my.ORCID http://orcid.org/0000-0001-8176-3939
Noor Diyana OsmanDepartment of Biomedical Imaging, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Pulau Pinang, Malaysia.
Rohayu HamiDepartment of Community Health, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Bertam, 13200, Kepala Batas, Pulau Pinang, Malaysia.
Yasser S AlajeramiMedical Imaging Department, Applied Medical Sciences Faculty, Al Azhar University-Gaza, P.O. Box 1277, Gaza City, Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComputerized tomography (CT) scans for COVID-19 diagnosis have increased throughout the pandemic. This growth has raised concerns about the potential radiation-induced cancer risk. This study aimed to estimate the effective dose (ED) and lifetime attributable risk (LAR) of cancer incidence and mortality associated with a single non-contrast chest CT scan for COVID-19 pneumonia diagnosis.

methodsA retrospective analysis included 522 consecutive COVID-19 patients who underwent a single non-contrast chest CT at Gaza Strip hospitals (September 1, 2020-September 30, 2022). The ImPACT CT Dosimetry spreadsheet (Version 1.0.4) was used to estimate organ and effective doses. The XrayRisk.com calculator was used for calculating the LAR of cancer incidence from a single chest CT.

resultsThe study analyzed non-contrast chest CT scans of 522 patients, with a mean age of 50.9 ± 15.8 years, and 239 males. The mean ED was 3.6 mSv, with the highest organ doses in the lungs and breast. Female patients were at a higher risk of cancer, with a higher risk in younger age groups. The mean LAR of lung cancer incidence was 5.8 per 100,000 males, while breast cancer incidence was 6.6 per 100,000 females. The whole-body ED of a single non-contrast chest CT is equivalent to 12 chest radiography series and three mammography screenings, or approximately four months of natural background radiation.

conclusionChest CT scans for COVID-19 patients carry a low but measurable cancer risk, particularly for younger and female patients. The long-term health impacts of such exposure should be closely monitored.

Indexed as

COVID-19Neoplasms, Radiation-InducedRadiation DosageTomography, X-Ray ComputedAdultAgedFemaleHumansIncidenceLung NeoplasmsMaleMiddle AgedRetrospective StudiesSARS-CoV-2ChestCOVID-19Radiation-induced cancerSpiral Computed Tomography

Identifiers

PMID40779137
PMCPMC12578716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.