Evidence map›Paper›PMID 40778962›Full record

ReviewProbiotics and antimicrobial proteins2026

Synergistic Effect of Nanoparticles with Probiotics on Gastrointestinal Regenerative Medicine.

Seyedeh Mehrnaz Kouhbananinejad, Alireza Farsinejad, Arman Shahabi, Naghmeh Satarzadeh, Amir Reza Sadeghifar, Fatemeh Mahmoudi-Meymand, Mahla Sattarzadeh Bardsiri, Amin Sadeghi Dousari

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seyedeh Mehrnaz KouhbananinejadStem Cells and Regenerative Medicine Innovation Center, Kerman University of Medical Sciences, Kerman, Iran.
Alireza FarsinejadStem Cells and Regenerative Medicine Innovation Center, Kerman University of Medical Sciences, Kerman, Iran.
Arman ShahabiStem Cells and Regenerative Medicine Innovation Center, Kerman University of Medical Sciences, Kerman, Iran.
Naghmeh SatarzadehStem Cells and Regenerative Medicine Innovation Center, Kerman University of Medical Sciences, Kerman, Iran.
Amir Reza SadeghifarDepartment of Orthopedics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Fatemeh Mahmoudi-MeymandStem Cells and Regenerative Medicine Innovation Center, Kerman University of Medical Sciences, Kerman, Iran.
Mahla Sattarzadeh BardsiriStem Cells and Regenerative Medicine Innovation Center, Kerman University of Medical Sciences, Kerman, Iran.
Amin Sadeghi DousariStem Cells and Regenerative Medicine Innovation Center, Kerman University of Medical Sciences, Kerman, Iran. amin.sadeghidousari@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanomedicine has emerged as a prominent field with significant potential to transform the future of medicine, thereby attracting considerable attention from researchers worldwide. In various studies, nanoparticles with high potential as delivery systems have been used in combination with probiotics, microorganisms that have beneficial health effects when consumed in sufficient doses, in treating inflammatory bowel disease, including ulcerative colitis and Crohn's disease. Nanoparticles are synthesized by various methods, including biological, physical, and chemical, and depending on their size and structure, they produce different effects on the digestive system when combined with probiotics. The study demonstrates that combining various nanoparticles with specific probiotics can effectively modulate intestinal microbiota, reduce inflammation, enhance mucosal barrier function, and boost antioxidant activity, thereby aiding in the treatment of inflammatory digestive diseases. So, future research should further investigate the long-term safety, optimal dosing, and mechanisms of action of these nanoparticle-probiotic combinations in clinical settings to maximize therapeutic benefits.

Indexed as

Gastrointestinal TractNanoparticlesProbioticsRegenerative MedicineAnimalsGastrointestinal MicrobiomeHumansInflammatory Bowel DiseasesGastrointestinalNanoparticlesProbioticsRegenerative medicine

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.