Evidence map›Paper›PMID 40778851›Full record

ArticleThe Journal of cell biology2025

Context is everything: The role of polo-like kinase I during C. elegans oocyte meiosis.

Needhi Bhalla

Abstract read
In one paragraph

Article in The Journal of cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Needhi BhallaDepartment of Molecular, Cell and Developmental Biology, Sinsheimer Labs, University of California, Santa Cruz, Santa Cruz, CA, USA.ORCID 0000-0002-6859-0073

Funding

Supplement to support an undergraduate student on Cell Cycle Control in C. elegansR35GM141835 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI BHALLA, NEEDHI · 2021 to 2025
$2.5M
NIGMS NIH HHS R35 GM141835NIH HHS R35GM141835
6 · The paper itself

Abstract

Meiotic chromosome segregation in oocytes often relies on meiosis-specific modifications of mitotic molecular mechanisms to respond to the unique challenges of this asymmetric division. In this issue, Narula and Wignall (https://doi.org/10.1083/jcb.202503080) demonstrate how the conserved polo-like kinase in Caenorhabditiselegans, PLK-1, has been repurposed in unexpected ways to ensure accurate meiotic chromosome segregation during oogenesis.

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsCell Cycle ProteinsMeiosisOocytesProtein Serine-Threonine KinasesProto-Oncogene ProteinsAnimalsChromosome SegregationFemaleOogenesisPolo-Like Kinase 1Caenorhabditis elegans ProteinsCell Cycle Proteinsplk-1 protein, C elegansPolo-Like Kinase 1Protein Serine-Threonine KinasesProto-Oncogene Proteins

Identifiers

PMID40778851
PMCPMC12333586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.