Evidence map›Paper›PMID 40778806›Full record

ArticleJMIR medical informatics2025

A Machine Learning Algorithm With an Oversampling Technique in Limited Data Scenarios for the Prediction of Present and Future Restorative Treatment Need: Development and Validation Study.

Elina Väyrynen, Otso Tirkkonen, Henna Tiensuu, Jaakko Suutala, Vuokko Anttonen, Marja-Liisa Laitala, Katri Kukkola, Saujanya Karki

Abstract readValidation Study
In one paragraph

Article in JMIR medical informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elina VäyrynenResearch Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland.ORCID 0009-0000-6890-3810
Otso TirkkonenResearch Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland.ORCID 0009-0005-9654-7100
Henna TiensuuBiomimetics and Intelligent Systems Group, Faculty of Information Technology and Electrical Engineering, University of Oulu, Oulu, Finland.ORCID 0000-0002-6026-9509
Jaakko SuutalaBiomimetics and Intelligent Systems Group, Faculty of Information Technology and Electrical Engineering, University of Oulu, Oulu, Finland.ORCID 0000-0002-6605-0057
Vuokko AnttonenResearch Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland.ORCID 0000-0002-3804-1858
Marja-Liisa LaitalaResearch Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland.ORCID 0000-0001-7323-9862
Katri KukkolaOptoelectronics and Measurement techniques, Faculty of Information Technology and Electrical Engineering, University of Oulu, Oulu, Finland.ORCID 0000-0002-2589-7251
Saujanya KarkiResearch Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland.ORCID 0000-0002-3160-8137

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUntreated dental caries is the most common health condition worldwide. Therefore, new strategies need to be developed to reduce the manifestations of dental caries.

objectiveThis study aimed to develop and test a machine learning (ML) algorithm for detecting present and predicting future carious lesions in the adolescent population using a set of easy-to-collect predictive variables. In addition, this study aimed to deal with an imbalanced and small dataset using an oversampling method.

methodsThis population-based study was conducted among secondary schoolchildren, aged between 13 and 17 years, from the northern parts of Finland in 2022. After meeting the inclusion criteria, a total of 218 participants were included in this study. The inclusion criteria consisted of participants having completed a web-based risk assessment questionnaire and having undergone a clinical examination at public health care services. Dental caries (International Caries Detection and Assessment System [ICDAS] scores of 4, 5, and 6; ie, ICDAS 4-6) and active initial caries (ICDAS 2+, 3+) were considered as outcomes. Several predictors, such as behavioral and dietary habits, were included. An extreme gradient boosting model was developed, tested, and assessed for its predictive performance. A 4-fold cross-validation was performed using the nested resampling technique. The random oversampling examples method and the k-nearest neighbors classifiers were used for all 4 folds. The mean (SD) performance of all the folds was computed.

resultsDental caries (ICDAS 2+,3+,4-6) were prevalent in 65.6% (143/218) of the participants. The mean area under the curve was 0.77 (SD 0.04) and the mean F

conclusionsOn the basis of the performance metrics, the ML algorithm developed and tested in this study can be considered good. The ML algorithm could serve as a cost-effective screening tool for dental professionals to identify the risk of future restorative treatment needs. However, future studies with longitudinal cohorts and longitudinal data, along with external validation for generalizability, are needed to validate our model.

Indexed as

AlgorithmsDental CariesMachine LearningAdolescentFemaleFinlandHumansMaleRisk AssessmentSurveys and Questionnairescaries managementdental cariesdentistrymachine learningoral health

Identifiers

PMID40778806
PMCPMC12426571

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.