Evidence map›Paper›PMID 40778699›Full record

ArticleInvestigative ophthalmology & visual science2025

Adaptive Optics and Multimodal Retinal Imaging for Postoperative Evaluation in Patients With Epiretinal Membrane.

Yuzhu Gao, Yifan Zhang, Yunxia Gao, Kefan Mou, Yilin Liu, Hanyue Xu, Shulei Man, Yi Chen, Lin Chen, Yufan Huang and 4 more

Abstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yuzhu GaoDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yifan ZhangDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yunxia GaoDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Kefan MouDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yilin LiuDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Hanyue XuDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Shulei ManDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yi ChenDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Lin ChenDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yufan HuangDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jingqi AnDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Tianpeng HuoDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jie ZhangAdvanced Ophthalmology Laboratory (AOL), Robotrak Technologies, Nanjing, Jiangsu, China.
Ming ZhangDepartment of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate adaptive optics scanning laser ophthalmoscope (AO-SLO) features and identify their multimodal retinal imaging characteristics using AO-SLO, swept-source optical coherence tomography (SS-OCT), and color fundus photography in patients undergoing surgery for epiretinal membrane (ERM), and to provide valuable insights into the mechanism underlying postoperative ERM progression. Methods: Patients with ERM underwent multimodal retinal imaging following surgery, including color fundus photography, SS-OCT, and AO-SLO. AO-SLO features were characterized, and their corresponding multimodal retinal imaging findings were analyzed. Results: Seventeen eyes from 17 postoperative ERM patients were included in this pilot study (mean age [SD], 68.06 [8.26] years; 12 female [70.6%]). Seven categories of AO-SLO features were identified in patients with ERM after surgery. The most common features were granular membrane (n = 17 [100%]), waxy membrane (n = 12 [70.6%]), and microcysts (n = 12 [70.6%]), after dissociated optic nerve fiber layer (n = 11 [64.7%]), microfolds (n = 6 [35.3%]), punctate reflectivity (n = 6 [35.3%]), and retinal folds (n = 5 [29.4%]). Conclusions: AO-SLO imaging provides detailed insights into retinal microstructural changes after surgery for ERM. Further longitudinal studies tracking AO-SLO features over time and integrating multimodal retinal imaging modalities could enhance our understanding of retinal restoration processes and improve the prediction of surgical outcomes in ERM.

Indexed as

Epiretinal MembraneMultimodal ImagingOphthalmoscopyRetinaTomography, Optical CoherenceVitrectomyAgedFemaleHumansMaleMiddle AgedPhotographyPilot ProjectsPostoperative PeriodVisual Acuity

Identifiers

PMID40778699
PMCPMC12347183

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.