Evidence map›Paper›PMID 40778352›Full record

ArticleFrontiers in neuroscience2025

The effect of musical sensory orientation training in improving consciousness level in patients with disorders of consciousness: a pilot study.

Jiayi Gu, Wei Long, Siqin Zeng, Liang Qin, Yi Dong, Cuini Fang, Xiaoying Zhang

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07544602 (Music Therapy for Comatose Brain Injured Patients), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07544602 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Music Therapy for Comatose Brain Injured Patients

Typeobservational_patient_registrySponsorMercy Health OhioRan2026 to 2028Enrolled35ConditionsTraumatic Brain Injury
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jiayi GuDepartment of Rehabilitation, Hunan Provincial People's Hospital (The first Affiliated Hospital of Hunan Normal University), Changsha, China.
Wei LongDepartment of Rehabilitation, Hunan Provincial People's Hospital (The first Affiliated Hospital of Hunan Normal University), Changsha, China.
Siqin ZengDepartment of Neurological Rehabilitation, Hunan Rehabilitation Hospital, Changsha, China.
Liang QinDepartment of Rehabilitation, Hunan Provincial People's Hospital (The first Affiliated Hospital of Hunan Normal University), Changsha, China.
Yi DongDepartment of Rehabilitation, Hunan Provincial People's Hospital (The first Affiliated Hospital of Hunan Normal University), Changsha, China.
Cuini FangDepartment of Rehabilitation, Hunan Provincial People's Hospital (The first Affiliated Hospital of Hunan Normal University), Changsha, China.
Xiaoying ZhangSchool of Rehabilitation Medicine, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Musical sensory orientation training (MSOT) is an innovative technique to improve the state of consciousness and cognitive function. Compared with traditional arousal therapies, MSOT offers a non-invasive, safe, and easily operable alternative with no side effects. This study aimed to conduct a preliminary investigation into the effect of MSOT in improving consciousness levels in patients with DoC (Disorders of Consciousness), as well as the feasibility of its clinical application, thereby providing reference for future large-sample randomized controlled studies. Methods: We recruited 42 participants between March 2024 to March 2025, dividing them into two groups: a control group of 21 patients who received conventional treatment for DoC and watched videos of family/friends' activities and short videos, and an intervention group of 21 patients who received MSOT along with conventional treatment. Patients in both groups were assessed at baseline, week 5 and week 8 of the intervention. Results: The MSOT group showed significant improvement in Coma Recovery Scale-Revised (CRS-R) subscale and total scores over time (baseline, week 5, week 8). At week 8, the MSOT group demonstrated significantly higher CRS-R scores in communication function and arousal level compared to the control group. Behavioral observations in the MSOT group revealed significantly higher frequencies of name response, sound source tracking, and command-following behaviors. Conclusion: The results of this study demonstrate that MSOT exhibits certain effect in improving consciousness levels in patients with DoC and demonstrates feasibility in clinical implementation. Extending the intervention duration in future studies may amplify its therapeutic effects.

Indexed as

CRS-Rdisorders of consciousnessMSOTmusic therapypilot study

Identifiers

PMID40778352
PMCPMC12330211

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.