Evidence map›Paper›PMID 40778287›Full record

ArticleFrontiers in systems neuroscience2025

Neural network modeling of psychoanalytic concepts.

Daniel S Levine, Ana Maria C Aleksandrowicz, Ana Luiza S Verissimo Lopes

Abstract read
In one paragraph

Article in Frontiers in systems neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel S LevineDepartment of Psychology, University of Texas at Arlington, TX, United States.
Ana Maria C AleksandrowiczFIOCRUZ, Rio de Janeiro, Brazil.
Ana Luiza S Verissimo LopesUNIRIO, Rio de Janeiro, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Techniques used over decades in brain-based neural network modeling are applied to understanding processes involved in psychoanalysis. Behavioral change is interpreted as a transition, using simulated annealing, from a less to a more optimal attractor in a competitive-cooperative dynamical system that includes analogs of the amygdala, prefrontal cortex, and hypothalamus, and the neurotransmitter norepinephrine. The article explores how psychoanalysis can facilitate the quest for the life that is as meaningful as possible. The resulting network theory allows for new understanding of several traditional Freudian concepts. The theory provides insights about the life and death drives. It also helps us understand object and narcissistic libido, and the contrast of healthy forms of libido based on autonomy vs. unhealthy forms based on dependence. This inquiry relates to the balance between self-interest and empathy, mediated by various areas of the limbic system. It illuminates transference, which involves both an emotional and intellectual relationship between the analyst and analysand, mediated by cognitive-emotional interactions in amygdala and orbitofrontal cortex. Sublimation, or redirection of socially inappropriate urges toward more appropriate behaviors, is interpreted via lateral inhibition between representations of similar complex behaviors.

Indexed as

amygdalabrainegohypothalamusneural networksprefrontal cortexpsychoanalysis

Identifiers

PMID40778287
PMCPMC12328427

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.