Evidence map›Paper›PMID 40778110›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2025

Is Routine Neuroimaging Needed in Adult-Onset Isolated Cervical Dystonia?

Elina Myller, Oskari Korhonen, Juho Joutsa

Abstract read
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Neuroimaging in Tremor.Seminars in neurology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elina MyllerTurku Brain and Mind Center, Clinical Neurosciences, University of Turku, Turku, Finland.ORCID 0000-0001-7591-1990
Oskari KorhonenTurku Brain and Mind Center, Clinical Neurosciences, University of Turku, Turku, Finland.
Juho JoutsaTurku Brain and Mind Center, Clinical Neurosciences, University of Turku, Turku, Finland.ORCID 0000-0002-3457-9415

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Clinical practices regarding neuroimaging in isolated cervical dystonia vary across countries and there are no published studies investigating the need of routine neuroimaging in this patient population. Objectives: To investigate if structural neuroimaging is needed in patients with isolated cervical dystonia. Methods: Patients with adult-onset cervical dystonia were identified from a systematic search of the medical records of Turku University Hospital 1996-2022. Clinical and structural neuroimaging data were reviewed by the investigators to evaluate the etiology of dystonia, specifically to identify cases of secondary dystonia caused by structural brain abnormalities. Results: 365 patients with cervical dystonia without other movement disorders with presumed idiopathic or uncertain etiology prior to brain imaging were identified. 282 (77.3%) were scanned using head MRI or CT. Acquired brain lesions were identified in nine (2.5% of all patients) and were significantly more common in patients with vs. without (i.e. isolated) other neurological features ( Conclusions: Routine neuroimaging is not necessary in patients with adult-onset isolated cervical dystonia. Highlights: Studies investigating the need of structural neuroimaging in isolated, adult-onset cervical dystonia are scarce and opinions on this issue are divided among experts.In this study, we reviewed clinical and imaging data of all patients with cervical dystonia with presumed idiopathic or uncertain etiology prior to brain imaging treated at a regional tertiary care hospital between 1996-2022 to investigate the yield of structural brain imaging in these patients.Of the included 365 patients, none showed evidence of progressive neurodegeneration underlying the symptoms and only six (1.6%) showed acquired brain lesions that were considered possibly or likely causal for cervical dystonia.All the six patients with possible or likely lesion-induced cervical dystonia showed cervical dystonia combined with other neurological features, indicating that routine neuroimaging is not needed in isolated, adult-onset cervical dystonia.

Indexed as

BrainNeuroimagingTorticollisAdultAgedFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedTomography, X-Ray ComputedCervical dystonianeuroimaging

Identifiers

PMID40778110
PMCPMC12330805

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.