Evidence map›Paper›PMID 40778092›Full record

ArticleJPRAS open2025

Analgesia in gender-affirming mastectomy: Intraoperative pectoral blocks are equally effective as preoperative, ultrasound-guided PECS I/II blocks.

Puja Jagasia, Andrea Battistini, Stephan Kienzel, Sumanas Jordan, Marco Ellis

Abstract read
In one paragraph

Article in JPRAS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Puja JagasiaDivision of Plastic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.
Andrea BattistiniDivision of Plastic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.
Stephan KienzelDepartment of Anesthesiology, Northwestern Memorial Hospital, Chicago, IL, USA.
Sumanas JordanDivision of Plastic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.
Marco EllisDivision of Plastic Surgery, Northwestern Memorial Hospital, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pectoral nerve blocks I and II (PECS I and II) can be given preoperatively under ultrasound guidance by an anesthesiologist or intraoperatively by a surgeon for postoperative pain control. A comparison of analgesia provided by preoperative versus intraoperative PECS blocks could help surgeons decide which method is most effective while optimizing resources. Methods: A retrospective review of patients receiving gender-affirming mastectomies at a single institution was conducted from 2018 to 2024. PECS I/II blocks were delivered intraoperatively before August 2023 and preoperatively thereafter. Twenty mL total of 0.25 % bupivacaine with epinephrine was used for PECSI+II blocks. Analgesic effect was measured with opioid consumption (MME) and patient-reported pain score in the PACU. The need for additional opioid medications after discharge was also evaluated. Results: A total of 438 subjects were included, with 84.5 % (370/438) in the intraoperative block group and the remaining 15.5 % (68/438) in the preoperative block group. Opioid consumption did not differ between the two groups (intraoperative: 13.1 ± 6.91 MME vs. preoperative: 12.7 ± 5.32 MME, Conclusion: Intraoperative PECS I/II blocks should be utilized over preoperative, ultrasound-guided PECS I/II blocks in the setting of gender-affirming mastectomy to provide effective analgesia while optimizing resource utilization and minimizing costs.

Indexed as

Gender-affirming careGender-affirming mastectomyGender-affirming surgeryNerve blockPECSPectoral nerve block

Identifiers

PMID40778092
PMCPMC12328835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.