Evidence map›Paper›PMID 40777955›Full record

ArticleAfrican health sciences2024

Factors associated with acute kidney injury and outcomes in patients with malaria in a district hospital in Rwanda.

Larrisa Umuhire, Violette Dushimiyimana, Michel Nkuranyabahizi, Flavien Ngendahayo, Jean Claude Shyaka, Innocent Ngerageze, Lakshmi Rajeswaran, Geldine Chironda

Abstract read
In one paragraph

Article in African health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Larrisa UmuhireUniversity of Rwanda, College of Medicine and Health Sciences, School of Nursing and Midwifery, Kigali, Rwanda.
Violette DushimiyimanaUniversity of Rwanda, College of Medicine and Health Sciences, School of Nursing and Midwifery, Kigali, Rwanda.
Michel NkuranyabahiziUniversity of Rwanda, College of Medicine and Health Sciences, School of Nursing and Midwifery, Kigali, Rwanda.
Flavien NgendahayoUniversity of Rwanda, College of Medicine and Health Sciences, School of Nursing and Midwifery, Kigali, Rwanda.
Jean Claude ShyakaUniversity of Rwanda, College of Medicine and Health Sciences, School of Nursing and Midwifery, Kigali, Rwanda.
Innocent NgeragezeUniversity of Rwanda, College of Medicine and Health Sciences, School of Nursing and Midwifery, Kigali, Rwanda.
Lakshmi RajeswaranUniversity of Rwanda, College of Medicine and Health Sciences, School of Nursing and Midwifery, Kigali, Rwanda.
Geldine ChirondaUniversity of Rwanda, College of Medicine and Health Sciences, School of Nursing and Midwifery, Kigali, Rwanda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acute kidney injury (AKI) remains one of the complications of severe malaria. Evidence on associated factors and outcomes for patients with complicated malaria and AKI is limited in Rwanda. Aim: To assess the factors associated with acute kidney injury and outcomes in patients with malaria in a district hospital in Rwanda. Method: A retrospective study design was applied. A census sampling strategy was used to select 122 files of patients admitted as severe malaria patients in 2016-2017. A developed clinical audit form was used to collect data from patients' files. Both descriptive and inferential statistics were used to analyze data. Results: Among the confirmed severe malaria files, 44% of participants were over 50 years and 52.5% were males. The majority, (91.5%) had community-based health insurance and 16.3% had acute kidney injury. The significant associated clinical factors were dehydration (p=.01), high-grade fever (p=.002), profuse sweating (p=.034), vomiting (p=.043), and diarrhea (p=.025). Of the 20 patients who developed AKI, 55% completely recovered, 15% died and 30% of cases were transferred to the highest facilities for hemodialysis. Conclusion: The existence of AKI among severe malaria patients was evident with some recovering and others dying. There is a need for educating healthcare professionals, mostly at district hospitals about the diagnosis and management of AKI as a result of complicated malaria.

Indexed as

Acute Kidney InjuryMalariaAdolescentAdultAgedDehydrationFemaleFeverHospitals, DistrictHumansMaleMiddle AgedRetrospective StudiesRisk FactorsRwandaYoung AdultAcute kidney injurycomplications of malariasevere malaria

Identifiers

PMID40777955
PMCPMC12327107

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.