Evidence map›Paper›PMID 40777938›Full record

ArticleAfrican health sciences2024

Added prognostic value of fat attenuation index and CT-derived fractional flow reserve over plaque burden in suspected CAD patients without standard modifiable risk factors.

Yang Yu, Fuqian Guo, Yicheng Chen, Wenjun Bao, Caiying Li

Abstract read
In one paragraph

Article in African health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yang YuDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Fuqian GuoDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Yicheng ChenDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Wenjun BaoDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Caiying LiDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In this study, we aimed to investigate the added prognostic value of fat attenuation index (FAI) and CT-derived fractional flow (CT-FFR) over plaque burden in suspected coronary artery disease (CAD) patients without standard modifiable risk factors (SMuRFs). Methodology: A total of 260 consecutive suspected CAD subjects without SMuRFs who underwent first coronary computed tomography angiography (CCTA) were retrospectively collected. We calculated FAI, CT-FFR, and segment involvement score (SIS) from CCTA images. Cox regression models were used to assess the incremental prognostic value of FAI and CT-FFR. Results: During a median follow-up of 25.00 months, major adverse cardiovascular events (MACE) were observed in 40 (15.4%) patients. FAI ≥ -70.1, CT-FFR ≤ 0.80, and SIS ≥ 4.5 were associated with the increased rate of MACE ( Conclusion: In suspected CAD patients without SMuRFs, neither FAI nor CT-FFR independently added incremental prognostic value over plaque burden. Combining FAI and CT-FFR had added prognostic value and improved cardiovascular risk stratification.

Indexed as

Computed Tomography AngiographyCoronary Artery DiseaseFractional Flow Reserve, MyocardialPlaque, AtheroscleroticAgedCoronary AngiographyFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsTomography, X-Ray ComputedCoronary artery diseaseCT-derived fractional flow reservefat attenuation indexplaque burdenprognosisstandard cardiovascular risk factor

Identifiers

PMID40777938
PMCPMC12327134

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.