Evidence map›Paper›PMID 40777922›Full record

ArticleRoyal Society open science2025

A causal model of human growth and its estimation using temporally sparse data.

John A Bunce, Catalina I Fernández, Caissa Revilla-Minaya

Abstract read
In one paragraph

Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

John A BunceDivision of Anthropology, American Museum of Natural History, New York, NY, USA.ORCID https://orcid.org/0000-0003-4092-485X
Catalina I FernándezDepartment of Human Behavior, Ecology, and Culture, Max Planck Institute for Evolutionary Anthropology, Leipzig, Sachsen, Germany.ORCID https://orcid.org/0000-0001-8127-4115
Caissa Revilla-MinayaDivision of Anthropology, American Museum of Natural History, New York, NY, USA.ORCID https://orcid.org/0000-0001-6305-0062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Existing models of human growth provide limited insight into underlying mechanisms responsible for inter-individual and inter-population variation in children's growth trajectories. Building on general theories linking growth to metabolic rates, we develop a causal parametric model of height and weight growth incorporating a representation of human body allometry and a process-partitioned representation of ontogeny. This model permits separation of metabolic causes of growth variation, potentially influenced by nutrition and disease, from allometric factors, potentially under stronger genetic control. We estimate model parameters using a Bayesian multilevel statistical design applied to temporally dense height and weight measurements of U.S. children, and temporally sparse measurements of Indigenous Amazonian children. This facilitates a comparison of the contributions of metabolism and allometry to observed cross-cultural variation in the growth trajectories of the two populations, and permits simulation of the effects of healthcare interventions on growth. This theoretical model provides a new framework for exploring the causes of growth variation in our species, while potentially guiding the development of appropriate, and desired, healthcare interventions in societies confronting growth-related health challenges, such as malnutrition and stunting.

Indexed as

AllometryAmazoniaGrowthIndigenous PeoplesMetabolismOntogeny

Identifiers

PMID40777922
PMCPMC12329442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.