Evidence map›Paper›PMID 40777876›Full record

ArticlePrzeglad menopauzalny = Menopause review2025

Effect of lifestyle changes on liver enzymes, triglycerides, sex hormones, and daytime sleepiness in polycystic ovarian syndrome women with obstructive sleep apnea and fatty liver - a randomized controlled trial.

Ali Mohamed Ali Ismail, Nehad Mohamed AbdElnabi Mousa, Sami Kamal Mohamed Elgendy, Asmaa M Al-Emrany, Orchid Saber AbdelFadil Saber, Sahar Mohamed Adel Elhakk, Dina Mohamed, Heba Ahmed Mousa Ghaleb

Abstract read
In one paragraph

Article in Przeglad menopauzalny = Menopause review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ali Mohamed Ali IsmailDepartment of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
Nehad Mohamed AbdElnabi MousaDepartment of Physical Therapy of Musculoskeletal Disorders and it's Surgeries, Horus University, New Damietta, Egypt.
Sami Kamal Mohamed ElgendyDepartment of Physical Therapy for Internal Medicine and Elderly, Faculty of Physical Therapy, Modern University for Technology and Information, Cairo, Egypt.
Asmaa M Al-EmranyDepartment of Physical Therapy for Internal Medicine and Geriatrics, Faculty of Physical Therapy, October University for Modern Sciences and Arts, 6 October City, Giza, Egypt.
Orchid Saber AbdelFadil SaberDepartment of Physical Therapy for Surgery and Burns, Faculty of Physical Therapy, Nahda University, Beni Suef, Egypt.
Sahar Mohamed Adel ElhakkDepartment of Basic Science, Faculty of Physical Therapy, Galala University, Suez, Egypt.
Dina MohamedDepartment of Physical Therapy for Women's Health, Faculty of Physical Therapy, Galala University, Suez, Egypt.
Heba Ahmed Mousa GhalebDepartment of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Lifestyle changes are one of the main therapeutic approaches for women with polycystic ovarian syndrome (PCOS), non-alcoholic fatty liver disease (NAFLD), and obstructive sleep apnea (OSA). This 8-week study aimed to assess the effect of lifestyle modifications on liver enzymes, triglycerides (TG), sex hormones, and daytime sleepiness in PCOS women with NAFLD and mild and moderate OSA. Material and methods: This study included 40 women. The included obese PCOS women with OSA and NAFLD were assigned randomly to the study group and control group ( Results: A significant improvement in the value of all outcomes was achieved in both PCOS groups, but the improvements were high in the study group. Also, the designed between-group comparison of post values of PCOS women's outcomes showed a significant improvement in the study group. Conclusions: Adding eight weeks of free-walking exercise to LCD and administration of metformin resulted in significantly greater improvements in PCOS than LCD and administration of metformin alone in women with NAFLD and OSA.

Indexed as

dietnon-alcoholic fatty liverobstructive sleep apneapolycystic ovarian syndromeweight loss

Identifiers

PMID40777876
PMCPMC12327225

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.