Evidence map›Paper›PMID 40777818›Full record

ArticleJournal of clinical biochemistry and nutrition2025

Andrographolide derivative CX-10 alleviates ulcerative colitis by modulating autophagy and cellular stress.

Zhengshi Chen, Yongheng He, Yi Hong, Feng Yu, Tianyun Gong, Xiaoxiao Tong

Abstract read
In one paragraph

Article in Journal of clinical biochemistry and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhengshi ChenDepartment of Anorectal, Tongde Hospital of Zhejiang Province, Gucui Road, Hangzhou, Zhejiang Province, 310000, China.
Yongheng HeDepartment of Anorectal, Hunan Academy of Traditional Chinese Medicine Affiliated Hospital, Shaoshan Middle Road, Changsha City, Hunan Province, 410006, China.
Yi HongDepartment of Anorectal, Hunan Academy of Traditional Chinese Medicine Affiliated Hospital, Shaoshan Middle Road, Changsha City, Hunan Province, 410006, China.
Feng YuDepartment of Anorectal, Tongde Hospital of Zhejiang Province, Gucui Road, Hangzhou, Zhejiang Province, 310000, China.
Tianyun GongDepartment of Anorectal, Tongde Hospital of Zhejiang Province, Gucui Road, Hangzhou, Zhejiang Province, 310000, China.
Xiaoxiao TongDepartment of Anorectal, Tongde Hospital of Zhejiang Province, Gucui Road, Hangzhou, Zhejiang Province, 310000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is a debilitating inflammatory bowel disease that poses significant challenges in clinical management. Despite existing therapies, many patients fail to achieve adequate symptom relief, underscoring the need to address the underlying mechanisms contributing to the pathogenesis of UC.

Indexed as

Andrographis paniculataandrographolideautophagyROSulcerative colitis

Identifiers

PMID40777818
PMCPMC12326248

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.