ReviewFundamental research2025
Intelligent nanozymes: Biomimetic design, mechanisms and biomedical applications.
Review in Fundamental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Immunomodulatory Nanozymes as Programmable Redox-Immune Set-Point Regulators.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Engineering nanozymes for cancer theranostics: Chemical design, catalytic intelligence, and translational oncology frontiers.Translational oncology · 2026Review
- Living Inorganic Nanomaterials: Design, Preparation, and Biomedical Applications.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Recent advances in metal sulfide nanozymes for sensing.RSC advances · 2026Review
- Eco-Nanozymology: A Catalytic Paradigm Integrating Energy, Environment, and Ecology.Nano-micro letters · 2026Review
- Multidimensional Unraveling Insights from an Enzyme-Nanozyme Cascade-Based Electrochemical Biosensor for Screening Microplastic Neurotoxicity.Environment & health (Washington, D.C.) · 2026Article
- Membrane-camouflaged nanoparticle alleviates intervertebral disc degeneration via oxidative stress suppression and autophagy activation.Materials today. Bio · 2026Article
- Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Synergistic Intra- and Inter-Nanozyme Electron Transfer through Interfacial Assembly for Enhanced Multi-Enzyme Activity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Precision-Engineered Silver Single-Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Nanozyme-Based Anti-Inflammatory Strategies in Cardiovascular Disease Management: Clinical Prospects and Challenges.International journal of nanomedicine · 2026Review
- In situ forming hydrogels for colorectal cancer therapy.Materials today. Bio · 2025Review
- Advances in methods for rapid detection of Staphylococcus aureus and methicillin-resistant S. aureus.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025Review
- Organic-Dominated Nanozymes for Pesticide Detection: Toward Sustainable Agricultural Monitoring.Journal of agricultural and food chemistry · 2025Review
- Deep Learning-Enhanced Nanozyme-Based Biosensors for Next-Generation Medical Diagnostics.Biosensors · 2025Review
- Nanomedicine in cardiovascular and cerebrovascular diseases: targeted nanozyme therapies and their clinical potential and current challenges.Journal of nanobiotechnology · 2025Review
- Biomaterials and materiobiology as the continuous powerhouse of biomedical innovation for our aging society.Fundamental research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanozymes are a unique class of nanomaterials that possess intrinsic enzymatic properties, exhibiting similar reaction kinetics to natural enzymes. As enzyme substitutes in various biomedical applications, nanozymes offer numerous advantages, including low cost, tunable catalytic activity, and exceptional stability. However, their catalytic activities are typically lower than those of natural enzymes, and the lack of precise control over their functional modulation limits their therapeutic potential. To address these challenges, the biomimetic and intelligent design of nanozymes has been introduced as a critical concept for enhancing their functionality. In this review, we will explore the importance of biomimetic design in the development of intelligent nanozymes. We will first introduce the foundational principles and strategies for their targeted design, followed by an overview of recent advances in the regulatory mechanisms and biomedical applications of intelligent nanozymes. Lastly, we will highlight the current limitations in this research field and propose future directions. With continued progress in biomimetic and intelligent design, nanozymes are poised to accelerate their clinical translation and large-scale commercialization, further expanding their potential in therapeutic applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.