Evidence map›Paper›PMID 40777708›Full record

ArticleCureus2025

Autoimmune Hemolytic Anemia as an Initial Manifestation of Splenic Marginal Zone Lymphoma.

Neeti Nachammai K M, Vengadakrishnan K, Suja Lakshmanan, Saajid Anwar

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Neeti Nachammai K MGeneral Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Vengadakrishnan KGeneral Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Suja LakshmananInternal Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Saajid AnwarGeneral Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune hemolytic anemia (AIHA) is caused by autoantibodies that target and destroy the individual's own red blood cells (RBCs). Warm AIHA is due to antibodies that are active at body temperature and are the most common type of AIHA. Herein, we report a 49-year-old woman who presented with breathlessness, easy fatiguability, and palpitations with blood picture showing severe anemia requiring multiple blood transfusions, leucocytosis, Direct Coombs Test (DCT) positivity, and elevated lactate dehydrogenase (LDH). The patient later developed increasing leukocytosis, for which bone marrow biopsy and immunophenotyping using flow cytometry were done, confirming the presence of underlying splenic marginal zone lymphoma resulting in secondary AIHA. The patient was referred to the hematology department and was started on treatment with steroids and rituximab.

Indexed as

autoimmune hemolytic anemia (aiha)hemolytic anemianon-hodgkin lymphomasplenic marginal zone lymphomawarm autoimmune hemolytic anemia

Identifiers

PMID40777708
PMCPMC12330171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.