Evidence map›Paper›PMID 40777684›Full record

ArticleCureus2025

A Case of Sickle Cell Beta Thalassemia and Recurrent Septicemia.

David I LeRoy, Elaine Ognjanovski, Amaani Desai, Anthony V Cook, Rafael Barretto

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David I LeRoyInternal Medicine, Henry Ford Health System - Warren, Warren, USA.
Elaine OgnjanovskiInternal Medicine, Henry Ford Health System - Warren, Warren, USA.
Amaani DesaiInternal Medicine, Henry Ford Health System - Warren, Warren, USA.
Anthony V CookInternal Medicine, Henry Ford Health System - Warren, Warren, USA.
Rafael BarrettoInternal Medicine, Henry Ford Health System - Warren, Warren, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sickle cell anemia and beta-thalassemia are among the most common hemoglobin disorders. They are characterized by abnormal hemoglobin production, leading to ineffective erythropoiesis and severe anemia. Compound forms, such as sickle cell beta-thalassemia (HbS/β-thalassemia), may experience a wide range of complications, including impaired splenic function and increased susceptibility to infections. In this case report, we describe the case of a 57-year-old female patient with sickle cell/beta0-thalassemia (Sß0) with frequent and prolonged hospital admissions for sepsis complicated by recurrent liver abscess requiring multiple procedures for intrahepatic drainage. This patient was found to have an abscess with cholelithiasis, with a multiseptated hypodense collection within the liver. Recurrent liver abscesses are rare and underreported in this population. This case highlights the need for further research to clarify pathophysiology and ultimately improve management.

Indexed as

adult sickle cell anemiahepatic abscessrecurrent sepsissepsissickle cell beta-thalassemia

Identifiers

PMID40777684
PMCPMC12330776

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.