ArticleCureus2025
Acute Promyelocytic Leukemia in a Patient With Sickle Cell Hemoglobin D Disease: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- When Blood Disorders Meet Cancer: Uncovering the Oncogenic Landscape of Sickle Cell Disease.Journal of clinical medicine · 2025Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myeloid neoplasms can occur in patients with sickle cell disease; however, the underlying connection between the two remains unclear. These neoplasms, along with other cancers such as female breast cancer and male genital cancer, may arise de novo or secondarily due to chronic inflammation associated with sickling crises. This chronic inflammation, and its downstream effects, may lead to cytogenetic aberrations that increase the risk of developing myeloid neoplasms. Another potential risk factor is hydroxyurea, a medication commonly used to reduce the frequency of sickling crises, with some reported cases of associated myeloid malignancies. To explore this possible link, we present a case of acute promyelocytic leukemia in a patient with sickle cell hemoglobin D disease who had never received hydroxyurea.
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