ArticleCureus2025
Beyond Boundaries: Metastasis of Cervical Squamous Cell Carcinoma to the Kidney.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cervical squamous cell carcinoma (SCC) is an aggressive gynecological malignancy that commonly metastasizes to the lungs, liver, and bones; renal involvement is extremely rare. We report the case of a 68-year-old woman with a history of high-grade cervical SCC, treated a decade earlier with hysterectomy and bilateral salpingo-oophorectomy, who recently presented with right flank pain and hematuria. Imaging revealed a mass involving the bladder and right distal ureter causing hydronephrosis. She underwent a cystoscopy with right ureteral stenting and transurethral resection of the bladder tumor (TURBT). Intraoperative examination revealed a mass in the right lateral vaginal wall. Histopathological examination of the TURBT specimen revealed invasive high-grade non-papillary SCC infiltrating the bladder wall, with sparing of the urothelial mucosa. Immunohistochemistry confirmed human papillomavirus (HPV)-associated, Grade 3 (poorly differentiated) recurrent cervical SCC. A dimercaptosuccinic acid (DMSA) scan demonstrated a non-functioning right kidney, and due to recurrent infections, she underwent a robotic-assisted right nephrectomy. Pathological examination of the renal specimen confirmed metastatic cervical SCC. This case illustrates a rare metastatic pathway of cervical cancer and underscores the importance of multidisciplinary evaluation in complex clinical presentations.
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