Evidence map›Paper›PMID 40777644›Full record

ArticleFrontiers in public health2025

Metabolome-wide associations with short-term exposure to PM

Haoneng Hu, Quan Zhou, Kang Cao, Yu Jiang, Jianjun Xiang, Jing Wu, Jin Li, Zhiwei Chen, Shuling Kang, Dandan Zhu and 2 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Haoneng Hu *Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou, China.
Quan Zhou *Fujian Medical University Affiliated Center for Disease Control and Prevention, Fuzhou, China.
Kang Cao *Department of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou, China.
Yu JiangDepartment of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou, China.
Jianjun XiangDepartment of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou, China.
Jing WuDepartment of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou, China.
Jin LiDepartment of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou, China.
Zhiwei ChenFujian Medical University Affiliated Center for Disease Control and Prevention, Fuzhou, China.
Shuling KangFujian Medical University Affiliated Center for Disease Control and Prevention, Fuzhou, China.
Dandan ZhuQuanzhou Medical College, Quanzhou, China.
Huaying LinFujian Medical University Affiliated Center for Disease Control and Prevention, Fuzhou, China.
Chuancheng WuDepartment of Preventive Medicine, School of Public Health, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Emerging evidence links fine particulate matter (PM Methods: In this study, we enlisted the participation of 112 healthy older adults. We employed personal samplers to monitor the concentrations of pollutants throughout the study period. Furthermore, we conducted an untargeted metabolomic analysis of plasma samples using a liquid chromatograph mass spectrometer (LC-MS). A general linear regression model was utilized to investigate the significant relationships between metabolites and pollutants. Metabolic pathway enrichment analysis was performed to reveal the disturbed metabolic pathways related to PM Results: Our study demonstrated that short-term exposure to PM Conclusion: The plasma metabolome presents a promising resource for biomarkers and pathways, elucidating the biological mechanisms of PM

Indexed as

Air PollutantsEnvironmental ExposureMetabolomeParticulate MatterPolycyclic Aromatic HydrocarbonsAgedEnvironmental MonitoringFemaleHumansMaleMetabolomicsMiddle AgedAir PollutantsParticulate MatterPolycyclic Aromatic Hydrocarbonsmetabolic pathwaymetabolomicsolder adultsPAHsPM2.5

Identifiers

PMID40777644
PMCPMC12328383

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.