Evidence map›Paper›PMID 40777611›Full record

ArticleFrontiers in urology2025

Trends in the prevalence of pediatric lower urinary tract symptoms in a national claims database of privately insured patients, 2007-2016.

Raphael James Brosula, Pranaya Venkatapuram, Abby L Chen, Chiyuan A Zhang, Kathleen M Kan

Abstract read
In one paragraph

Article in Frontiers in urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raphael James BrosulaDepartment of Urology, Stanford University School of Medicine, Palo Alto, CA, United States.
Pranaya VenkatapuramDepartment of Urology, Stanford University School of Medicine, Palo Alto, CA, United States.
Abby L ChenDepartment of Urology, Stanford University School of Medicine, Palo Alto, CA, United States.
Chiyuan A ZhangDepartment of Urology, Stanford University School of Medicine, Palo Alto, CA, United States.
Kathleen M KanDepartment of Urology, Stanford University School of Medicine, Palo Alto, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pediatric lower urinary tract symptoms (LUTS) impact a significant number of children and families worldwide. Estimated prevalences rely on small cross-sectional studies, leading to inconsistent estimates. This study aims to characterize demographic and temporal trends in LUTS prevalence within a national claims database of privately insured individuals in the United States. Methods: We conducted a retrospective cohort study by reviewing the Merative™ MarketScan Results: We identified 1,625,538 patients aged 5-18 years with LUTS, representing 6% of the total population at risk, with a median age of 8.0 years. More patients in the cohort were female (66.1%), between 5-10 years old (57.9%), and resided in the Southern US (38.5%). The yearly prevalence of LUTS significantly increased from 1.8% to 2.1% yearly, and saw significant increases in females, 15-18 year old patients, and across several geographic regions. Comorbid constipation and ADHD within LUTS patients also significantly increased. Diagnostic coding practices remained stable. Conclusions: Families of patients with LUTS are increasingly seeking medical care for their condition. These results exceed similar estimates from previous longitudinal studies and can inform population-level intervention strategies. Further studies should investigate the impact of LUTS on healthcare resource utilization, including in non-privately insured populations.

Indexed as

administrative claimshealthcarelower urinary tract symptomspediatricsretrospective studiesurology

Identifiers

PMID40777611
PMCPMC12327348

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.