Evidence map›Paper›PMID 40777588›Full record

ArticleInternational journal of cardiology. Heart & vasculature2025

Recurrences of the infective endocarditis: clinical features and outcomes. Results from the Polish infective endocarditis registry (POL-ENDO).

Jakub W Orzech, Karina Zatorska, Maciej Grabowski, Małgorzata Misztal-Ogonowska, Dagmara B Orzech, Ilona Kowalik, Katarzyna Kurnicka, Magdalena Potapowicz-Krysztofiak, Edyta Płońska-Gościniak, Mariusz Gąsior and 1 more

Abstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jakub W OrzechDepartment of Valvular Heart Disease, National Institute of Cardiology, Warsaw, Poland.
Karina ZatorskaDepartment of Valvular Heart Disease, National Institute of Cardiology, Warsaw, Poland.
Maciej GrabowskiDepartment of Valvular Heart Disease, National Institute of Cardiology, Warsaw, Poland.
Małgorzata Misztal-OgonowskaDepartment of Valvular Heart Disease, National Institute of Cardiology, Warsaw, Poland.
Dagmara B OrzechDepartment of Valvular Heart Disease, National Institute of Cardiology, Warsaw, Poland.
Ilona KowalikClinical Research Support Center, National Institute of Cardiology, Warsaw, Poland.
Katarzyna KurnickaDepartment of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland.
Magdalena Potapowicz-KrysztofiakDepartment of Cardiology and Internal Diseases, Military Institute of Medicine-National Research Institute, Warsaw, Poland.
Edyta Płońska-GościniakDepartment of Cardiology, Pomeranian Medical University, Szczecin, Poland.
Mariusz Gąsior3 Department and Clinic of Cardiology, Faculty of Medical Sciences in Zabrze, Silesian Medical University, Katowice, Poland.
Tomasz HryniewieckiDepartment of Valvular Heart Disease, National Institute of Cardiology, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with prior infective endocarditis are associated with an increased risk of recurrence. Aims: This study aimed to assess the clinical profile and treatment results of recurrent IE patients in Poland and compare them to European recurrent IE profile. Methods: A prospective multicenter observational cohort study of recurrent IE and first-episode IE patients from 160 medical centers in Poland registered between August 2022 and August 2024 was conducted. Polish recurrent IE cases were compared with those recorded in the ESC-EORP EURO-ENDO registry. Results: Of a total of 1758 IE patients, recurrent IE patients (n = 371) were younger than first-episode IE (n = 1387) patients [58.2 ± 16.6 vs. 62.6 ± 16.2, p < 0.001] and predominated in Poland [21.1 % vs. 8.6 %, p < 0.001]. Dental treatment predisposed to IE recurrence [12.8 % vs. 5.5 %, p < 0.001]. Prosthetic valve IE predominated among recurrent IE patients [33.1 % vs. 19.7 %, p < 0.001]. Fever > 38° was observed less often among recurrent IE cases [34.8 % vs. 54.1 %, p < 0.001]. Negative blood culture predominated among recurrent IE cases [43.3 % vs. 27.2 %, p < 0.001]. Polish recurrent IE patients were rarely operated than European counterparts [55.2 % vs. 64.8 %, p = 0.032]. The embolic surgery indications were less prominent in Poland [0.08 % vs. 20.2 %, p < 0.001]. Conclusions: The IE recurrence rate in Poland is greater. Dental treatment and valve prosthesis predispose to recurrence of IE. Fever > 38° is less often observed among recurrent IE. Surgical treatment is underutilized among Polish recurrent IE patients. Embolic and uncontrolled infection indications for surgery was underrated in Poland. The IE recurrence is not associated with increased in-hospital mortality.

Indexed as

Infective endocarditisPolandRecurrenceRegistryValvular disease

Identifiers

PMID40777588
PMCPMC12329254

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.