Evidence map›Paper›PMID 40777448›Full record

ArticlebioRxiv : the preprint server for biology2025

Environmental and Maternal Imprints on Infant Gut Metabolic Programming.

Kine Eide Kvitne, Celeste Allaband, Jennifer C Onuora, Daniela Perry, Simone Zuffa, Lucas Patel, Vincent Charron-Lamoureux, Ipsita Mohanty, Kristija Sejane, Abubaker Patan and 24 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors.

Kine Eide KvitneSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-8118-7660
Celeste AllabandDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0003-1832-4858
Jennifer C OnuoraCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Daniela PerryDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Simone ZuffaSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-7237-3402
Lucas PatelDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Vincent Charron-LamoureuxSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-9440-7036
Ipsita MohantySkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-5311-6443
Kristija SejaneDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID 0009-0004-9643-0458
Abubaker PatanSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0003-1415-7829
Abdullah Al MahmudNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Tahmeed AhmedNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Diego G BassaniCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0001-6704-3820
Antonio GonzálezDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Davidson H HamerDepartment of Global Health, Boston University School of Public Health, Boston, MA, USA.ORCID 0000-0002-4700-1495
Rashidul HaqueNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Benjamin HoSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
Md Iqbal HossainNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Mohammad Shahidul IslamChild Health Research Foundation, Dhaka, Bangladesh.
Daniel McDonaldDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0003-0876-9060
Lisa G PellCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Huma QamarCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.
Daniel E RothCentre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada.ORCID 0000-0001-7742-0925
Samir SahaChild Health Research Foundation, Dhaka, Bangladesh.
Prakesh S ShahDepartment of Paediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-9920-0488
Md Muniruzzaman SiddiquiMohammadpur Fertility Services and Training Centre, Dhaka, Bangladesh.
Shafiqul Alam SarkerNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Shamima SultanaNutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
Sydney ThomasSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
Lindsey A BurnettDepartment of Obstetrics Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.
Shirley M TsunodaSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
Lars BodeDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Pieter C DorresteinSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
Rob KnightDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.

Funding

REPRODUCTIVE SCIENTIST TRAINING PROGRAMK12HD000849 · NICHD · WASHINGTON UNIVERSITY · PI Danny J Schust · 1988 to 2026
$33.2M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007198 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHI, NEIL C, INSEL, PAUL A · 1985 to 2024
$29.3M
The impact of ampicillin and breast milk oligosaccharides on the infant microbiome and immune functionsP50HD106463 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Lars Bode, CHRISTINA CHAMBERS · 2021 to 2026
$19.6M
Reverse Metabolomics for the Discovery of Disease Associated Microbial MoleculesR01DK136117 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PIETER C DORRESTEIN · 2023 to 2026
$2.9M
Developing Pediatric Clinical Pharmacologists for the Advancement of TherapeuticsT32HD087978 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIZET, VICTOR, TREMOULET, ADRIANA H · 2016 to 2025
$1.5M
Bill & Melinda Gates Foundation INV-015983NICHD NIH HHS K12 HD000849NICHD NIH HHS P50 HD106463NICHD NIH HHS T32 HD087978NIDDK NIH HHS R01 DK136117NIGMS NIH HHS T32 GM007198
6 · The paper itself

Abstract

Early life is a critical period for immune and metabolic programming, but developmental patterns remain underexplored in populations from low- and middle-income countries. Here, we profiled the microbiome and metabolome of 55 Bangladeshi mother-infant dyads over the first six months of life. Importantly, we observed an increase in microbially-derived bile amidates and

Identifiers

PMID40777448
PMCPMC12330730

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.