Evidence map›Paper›PMID 40777444›Full record

ArticlebioRxiv : the preprint server for biology2025

Sensory Entrained TMS (seTMS) enhances motor cortex plasticity.

J M Ross, L Forman, U Hassan, J Gogulski, J Truong, C C Cline, S Parmigiani, N-F Chen, J W Hartford, T Fujioka and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

J M RossDepartment of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.ORCID 0000-0002-7487-8946
L FormanDepartment of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.
U HassanDepartment of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.
J GogulskiDepartment of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.ORCID 0000-0001-7179-7828
J TruongDepartment of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.
C C ClineDepartment of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.ORCID 0000-0003-1442-8641
S ParmigianiDepartment of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.
N-F ChenDepartment of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.
J W HartfordDepartment of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.
T FujiokaWu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.
S MakeigSwartz Center for Computational Neuroscience, Institute for Neural Computation, University of California, San Diego, CA, USA.
A Pascual-LeoneDepartment of Neurology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-8975-0382
C J KellerDepartment of Psychiatry and Behavioral Sciences, Stanford University Medical Center, 401 Quarry Road, Stanford, CA, 94305, USA.ORCID 0000-0003-0529-3490

Funding

Multifocal transcranial current stimulation for cognitive and motor dysfunction in dementiaR01AG076708 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI MANOR, BRADLEY D., PASCUAL-LEONE, ALVARO · 2022 to 2024
$2.3M
Closing the loop: development of real-time, personalized brain stimulationR01MH126639 · NIMH · STANFORD UNIVERSITY · PI KELLER, COREY J · 2021 to 2024
$1.6M
NIA NIH HHS R01 AG076708NIMH NIH HHS R01 MH126639
6 · The paper itself

Abstract

Neural excitability fluctuates with sensory events, creating windows of opportunity to enhance brain stimulation. Repetitive transcranial magnetic stimulation (TMS), including intermittent theta burst stimulation (iTBS), is a promising treatment for neurological and psychiatric disorders, but does not account for fluctuations in neural excitability, likely contributing to variable outcomes. Sensory Entrained TMS (seTMS) leverages sensorimotor oscillations to enhance corticospinal responses, but the sustained effects as a repetitive protocol are unknown. We extend seTMS to iTBS, measuring motor-evoked potentials (MEPs) as a physiological readout. In a randomized crossover study comparing standard iTBS with sensory entrained iTBS (se-iTBS;

Indexed as

Electroencephalogram (EEG)Motor Evoked Potential (MEP)Non-invasive brain stimulation (NIBS)Transcranial magnetic stimulation (TMS)

Identifiers

PMID40777444
PMCPMC12330617

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.