Evidence map›Paper›PMID 40777439›Full record

ArticlebioRxiv : the preprint server for biology2025

Chemogenetic and optogenetic strategies for spatiotemporal control of split-enzyme-based calcium recording.

Yunlei Zhang, Brianna K Campmier, Akaash Sharma, Kelly N Eckartt, Scott T Laughlin

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yunlei ZhangDepartment of Chemistry Stony Brook University, Stony Brook, New York, USA.
Brianna K CampmierDepartment of Chemistry Stony Brook University, Stony Brook, New York, USA.
Akaash SharmaDepartment of Chemistry Stony Brook University, Stony Brook, New York, USA.
Kelly N EckarttDepartment of Chemistry Stony Brook University, Stony Brook, New York, USA.ORCID 0000-0002-0438-6436
Scott T LaughlinDepartment of Chemistry Stony Brook University, Stony Brook, New York, USA.ORCID 0000-0002-9134-1200

Funding

Opto- and chemogenetic neural activity recording with diverse reportersR01NS110771 · NINDS · STATE UNIVERSITY NEW YORK STONY BROOK · PI LAUGHLIN, SCOTT T. · 2019 to 2023
$1.7M
Neural activity integration during user defined epochs with modular reportersR21EY027578 · NEI · STATE UNIVERSITY NEW YORK STONY BROOK · PI LAUGHLIN, SCOTT T. · 2016 to 2017
$476k
NEI NIH HHS R21 EY027578NINDS NIH HHS R01 NS110771
6 · The paper itself

Abstract

Methods for monitoring physiological changes in cellular Ca

Identifiers

PMID40777439
PMCPMC12330574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.