Evidence map›Paper›PMID 40777375›Full record

ArticlebioRxiv : the preprint server for biology2025

Mono-mix strategy enables comparative proteomics of a cross-kingdom microbial symbiosis.

Sunnyjoy Dupuis, Usha F Lingappa, Samuel O Purvine, Lauren Chiang, Sean D Gallaher, Carrie D Nicora, Mary S Lipton, Sabeeha S Merchant

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Sunnyjoy DupuisDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.ORCID 0000-0001-5045-8659
Usha F LingappaCalifornia Institute for Quantitative Biosciences, University of California, Berkeley, CA 94720, USA.ORCID 0000-0001-5691-6788
Samuel O PurvineEarth and Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA.ORCID 0000-0002-2257-2400
Lauren ChiangDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.ORCID 0009-0002-8530-7839
Sean D GallaherCalifornia Institute for Quantitative Biosciences, University of California, Berkeley, CA 94720, USA.ORCID 0000-0002-9773-6051
Carrie D NicoraEarth and Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA.ORCID 0000-0003-2461-9548
Mary S LiptonEarth and Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA.ORCID 0000-0001-7749-0077
Sabeeha S MerchantDepartment of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.ORCID 0000-0002-2594-509X

Funding

Genetic Dissection of Cells and Organisms Training ProgramT32GM132022 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Nicole King, NOAH K WHITEMAN · 2019 to 2026
$5.2M
NIGMS NIH HHS T32 GM132022
6 · The paper itself

Abstract

Cross-kingdom microbial symbioses, such as those between algae and bacteria, are key players in biogeochemical cycles. The molecular changes during initiation and establishment of symbiosis are of great interest, but quantitatively monitoring such changes can be challenging, particularly when the microorganisms differ greatly in size or are intimately associated. Here, we analyze output from data-dependent acquisition (DDA) LC-MS/MS proteomics experiments investigating the well-studied interaction between the alga

Indexed as

chlorophyteDual-proteomicslabel-free quantitationmixed culturesrhizobiashotgun proteomics

Identifiers

PMID40777375
PMCPMC12330575

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.