Evidence map›Paper›PMID 40777350›Full record

ArticlebioRxiv : the preprint server for biology2025

Dynamin regulates PLK-1 localization and spindle pole assembly during mitosis.

Carter Dierlam, Livinus Anyanwu, Stephanie Held, Robert H Newman, Jyoti Iyer

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Carter DierlamDepartment of Cell Biology and Molecular Genetics, University of Maryland College Park, College Park, MD 20742.
Livinus AnyanwuDepartment of Chemistry and Biochemistry, University of Tulsa, Tulsa, OK 74104.
Stephanie HeldDepartment of Biology, North Carolina Agricultural and Technical State University, Greensboro, NC 27411.
Robert H NewmanDepartment of Biology, North Carolina Agricultural and Technical State University, Greensboro, NC 27411.
Jyoti IyerDepartment of Biology, North Carolina Agricultural and Technical State University, Greensboro, NC 27411.ORCID 0000-0002-0942-6919

Funding

Understanding connective tissue development and disease with PDGFR-driven..... P20GM103636 · NIGMS · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI THOMPSON, LINDA F · 2013 to 2023
$26.9M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Identification and characterization of chemical probes for interrogation of the NEK family of kinases in cancer (Diversity Supplement - Belgodere)R01CA273095 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUROW, MATTHEW E., DREWRY, DAVID HAROLD · 2022 to 2025
$2.9M
Redox regulation of protein kinase function: biochemical mechanisms and cellular consequencesR35GM153737 · NIGMS · NORTH CAROLINA AGRI & TECH ST UNIV · PI Robert Howard Newman · 2024 to 2026
$1.1M
NCI NIH HHS R01 CA273095NIGMS NIH HHS P20 GM103636NIGMS NIH HHS R35 GM153737NIH HHS P40 OD010440
6 · The paper itself

Abstract

Accurate cytokinesis is essential for maintaining genomic integrity. Although the GTPase dynamin has been well studied for its role in vesicular trafficking, its function during mitosis remains poorly understood. In this study, we uncover a novel role for the

Indexed as

cytokinesisdynaminmidbodymitosisPlk1

Identifiers

PMID40777350
PMCPMC12330643

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.