Evidence map›Paper›PMID 40777314›Full record

ArticlebioRxiv : the preprint server for biology2025

Protein Malnutrition Facilitates Intestinal Colonization with Highly Resistant

Thomas Holowka, Veronica Feijoli Santiago, Jamie Xiao, Mera F Liccione, Alisher Bimagambetov, Kenneth Walsh, Jason W Arnold, Kalisvar Marimuthu, Oon Tek Ng, Jonathan R Swann and 2 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thomas HolowkaDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-7244-6314
Veronica Feijoli SantiagoSchool of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Jamie XiaoDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Mera F LiccioneDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Alisher BimagambetovUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kenneth WalshDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jason W ArnoldDepartment of Molecular Genetics and Microbiology, Duke Microbiome Center, Duke University School of Medicine, Durham, North Carolina, USA.
Kalisvar MarimuthuNational Centre for Infectious Diseases, Singapore.
Oon Tek NgNational Centre for Infectious Diseases, Singapore.
Jonathan R SwannSchool of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
David van DuinDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Luther A BarteltDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT S. SANDLER · 1985 to 2026
$30.5M
INFECTIOUS DISEASE PATHOGENESIS TRAININGT32AI007151 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JULIANO, JONATHAN J · 1985 to 2024
$5.5M
Interactions of dietary protein intake and intestinal resident microbiota affecting susceptibility to persistent Giardia infection and Giardia mediated enteropathyR01AI151214 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BARTELT, LUTHER A · 2020 to 2024
$3.1M
Bacterial Characteristics of Community-associated Carbapenem-Resistant EnterobacteriaceaeR01AI143910 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VAN DUIN, DAVID · 2019 to 2023
$1.9M
NIAID NIH HHS R01 AI143910NIAID NIH HHS R01 AI151214NIAID NIH HHS T32 AI007151NIAID NIH HHS UM1 AI104681NIDDK NIH HHS P30 DK034987
6 · The paper itself

Abstract

Pediatric infections with Highly Resistant Enterobacterales (HRE), including

Identifiers

PMID40777314
PMCPMC12330750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.