Evidence map›Paper›PMID 40777209›Full record

ArticleEFSA journal. European Food Safety Authority2025

Re-evaluation of oxygen (E 948) and hydrogen (E 949) as food additives.

EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Lourdes Bastos, Polly Boon, Biagio Fallico, Reginald FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl-Kraupp and 13 more

Abstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Re-evaluation of oxygen (E 948) and hydrogen (E 949) as food additives.EFSA journal. European Food Safety Authority · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

EFSA Panel on Food Additives and Flavourings (FAF)
Laurence Castle
Monica Andreassen
Gabriele Aquilina
Maria Lourdes Bastos
Polly Boon
Biagio Fallico
Reginald FitzGerald
Maria Jose Frutos Fernandez
Bettina Grasl-Kraupp
Ursula Gundert-Remy
Rainer Gürtler
Eric Houdeau
Marcin Kurek
Henriqueta Louro
Patricia Morales
Sabina Passamonti
Josef Daniel Rasinger
Camilla Smeraldi
Samuele Di Ciano
Borana Dino
Elena Mazzoli
Ana Maria Rincon

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Panel on Food Additives and Flavourings (FAF) provides a scientific opinion re-evaluating the safety of oxygen (E 948) and hydrogen (E 949) as food additives. Their currently permitted use in food in the European Union (EU) is in all food categories, including in foods for infants and young children at quantum satis (QS). They can also be used in food additive preparations, food enzymes and nutrients also at QS. No interested business operators (IBOs) provided information in response to the call for data published by EFSA to support their re-evaluation. The original evaluation by the EU in 1990 indicated their use as packaging gases, and in the case of oxygen (E 948), also as propellant. The Panel considered the two gases to be of low toxicological concern when used as food additives and their dietary exposure very low. The Panel concluded that the use of oxygen (E 948) and hydrogen (E 949) as food additives does not raise a safety concern. The Panel made some recommendations for amending existing EU specifications for both oxygen (E 948) and hydrogen (E 949).

Indexed as

1333‐74‐07782‐44‐7E 948E 949food additiveshydrogenoxygen

Identifiers

PMID40777209
PMCPMC12329423

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.