Evidence map›Paper›PMID 40777121›Full record

ArticleFrontiers in oncology2025

A rare case report on esophageal squamous cell carcinoma metastatic to the pancreas.

Inderpreet Bhatti, Robert E Rogers, Benjamin L Witt, Chris Nevala-Plagemann, Jeffrey Patterson-Fortin

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Inderpreet BhattiDivision of Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, United States.
Robert E RogersDepartment of Pathology, University of Utah, Salt Lake City, UT, United States.
Benjamin L WittDepartment of Pathology, University of Utah, Salt Lake City, UT, United States.
Chris Nevala-PlagemannDivision of Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, United States.
Jeffrey Patterson-FortinDivision of Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic metastasis of esophageal squamous cell carcinoma is extremely rare. We describe a case of man aged 66 years who presented with a 3-month history of dysphagia. Esophagogastroduodenoscopy demonstrated an esophageal mass. Additional asymptomatic solitary lung and pancreatic masses were observed in the staging work-up for esophageal cancer, concerning for metastatic versus synchronous primary malignancy. Computed Tomography guided needle biopsy of the lung and pancreatic masses was performed. Given the difficulty to definitively histologically confirm both the lung and the pancreatic masses were metastasis from the primary esophageal cancer, next generation sequencing and tumor origin testing was performed. Tumor origin testing was indeterminate with the molecular profile inconclusive. Treatment was initiated with chemotherapy and immunotherapy.

Indexed as

esophageal cancerpancreatic metastasisrare metastasis sitessquamous cell carcinomatumor disseminationtumor origin identification

Identifiers

PMID40777121
PMCPMC12328172

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.