Evidence map›Paper›PMID 40777085›Full record

ReviewInternational journal of pharmaceutics: X2025

Multifunctional gold nanoclusters as next-generation theranostic platforms for disease management.

Yan Sun, Yining Chen, Xiaoyang Hu, Ai Liu, Lizhong He, Afang Dai, Tiansheng Wei, Shoucui Wang, Zibao Gan

Abstract readReview
In one paragraph

Review in International journal of pharmaceutics: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan SunKey Laboratory of Advanced Biomaterials and Nanomedicine in Universities of Shandong, Linyi University, Linyi 276000, China.
Yining ChenKey Laboratory of Advanced Biomaterials and Nanomedicine in Universities of Shandong, Linyi University, Linyi 276000, China.
Xiaoyang HuKey Laboratory of Advanced Biomaterials and Nanomedicine in Universities of Shandong, Linyi University, Linyi 276000, China.
Ai LiuKey Laboratory of Advanced Biomaterials and Nanomedicine in Universities of Shandong, Linyi University, Linyi 276000, China.
Lizhong HeSchool of Materials Science & Engineering, Xi'an Polytechnic University, Xi'an 710048, China.
Afang DaiKey Laboratory of Advanced Biomaterials and Nanomedicine in Universities of Shandong, Linyi University, Linyi 276000, China.
Tiansheng WeiKey Laboratory of Advanced Biomaterials and Nanomedicine in Universities of Shandong, Linyi University, Linyi 276000, China.
Shoucui WangKey Laboratory of Advanced Biomaterials and Nanomedicine in Universities of Shandong, Linyi University, Linyi 276000, China.
Zibao GanKey Laboratory of Advanced Biomaterials and Nanomedicine in Universities of Shandong, Linyi University, Linyi 276000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoclusters (GNCs), typically consisting of a few to a few hundred gold atoms with a core size below 3 nm, have emerged as revolutionary nanomaterials due to their diverse and tunable molecule-like properties, high photostability, and excellent biocompatibility. These advantages establish GNCs as next-generation theranostic platforms for precise nanomedicine applications. In this review, we summarize the typical synthesis methodologies, focus on their latest cutting-edge applications in disease management, including bioimaging, sensing, drug delivery, cancer, and other diseases. Finally, we discuss the challenges and opportunities associated with GNCs as theranostic agents. It is envisioned that this review aims to guide the rational design of GNC-based smart platforms and stimulate interdisciplinary innovation in personalized medicine.

Indexed as

DiseaseGold nanoclustersSynthesisTheranostics

Identifiers

PMID40777085
PMCPMC12329304

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.