Evidence map›Paper›PMID 40777052›Full record

ArticleiScience2025

Impaired neuromodulator crosstalk delays arousal-dependent astroglia Ca

Eunice Y Heo, Angelica Salinas-Birt, Liang Ye, Sanaz Sajadi, Mithun K Sarker, Yongjie Yang, Martin Paukert

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eunice Y HeoDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Angelica Salinas-BirtDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Liang YeDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Sanaz SajadiDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Mithun K SarkerDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Yongjie YangDepartment of Neuroscience, Tufts University, Boston, MA 02111, USA.
Martin PaukertDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

Funding

CNS Exosomes-Mediated Adaptive Immunity in Alzheimer's Disease (AD)R01AG078728 · NIA · TUFTS UNIVERSITY BOSTON · PI ALEXEI DEGTEREV, Yongjie Yang · 2022 to 2026
$4.4M
Astrolglia-Mediated Pathogenic Mechanisms in Fragile X Syndrome (FXS)R01MH106490 · NIMH · TUFTS UNIVERSITY BOSTON · PI YANG, YONGJIE · 2016 to 2025
$3.3M
Exosomal miRNA in neuron to astroglial communication in the CNSR01NS118747 · NINDS · TUFTS UNIVERSITY BOSTON · PI YANG, YONGJIE · 2020 to 2024
$2.2M
Dysfunctional Astroglial Exosome to (motor) Neuron Axon Signaling in ALSR01NS125490 · NINDS · TUFTS UNIVERSITY BOSTON · PI Yongjie Yang · 2022 to 2026
$2.1M
The Role of Astroglia in Brain State-Dependent Neural ActivityR01MH113780 · NIMH · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI PAUKERT, MARTIN · 2017 to 2021
$1.9M
Ethanol and brain state-dependent neural signalingR01AA025128 · NIAAA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI PAUKERT, MARTIN · 2017 to 2021
$1.7M
Integrated Graduate Training Program in Neuroscience, UTHSCSAT32NS082145 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI David A Morilak · 2013 to 2026
$1.5M
Behavioral state-dependent microglia Ca2+ dynamicsR21MH129960 · NIMH · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI PAUKERT, MARTIN · 2023 to 2024
$426k
NIAAA NIH HHS R01 AA025128NIA NIH HHS R01 AG078728NIMH NIH HHS R01 MH106490NIMH NIH HHS R01 MH113780NIMH NIH HHS R21 MH129960NINDS NIH HHS R01 NS118747NINDS NIH HHS R01 NS125490NINDS NIH HHS T32 NS082145
6 · The paper itself

Abstract

Cortical astrocyte Ca

Indexed as

Biological sciencesNatural sciencesNeuroscienceSystems neuroscience

Identifiers

PMID40777052
PMCPMC12329260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.