ArticleAdvances in radiation oncology2025
Salvage Irradiation for Ocular Adnexal Mucosa Associated Lymphoid Tissue Lymphoma Refractory to
Article in Advances in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Recent advances in infections as risk factors for lymphoma: a review of the effects of viral, bacterial, and fungal infections in lymphoma.Archives of microbiology · 2025Review
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Prospective trials show that Methods and Materials: Patients with stage IEA OAMZL diagnosed at our institution between 2005 and 2023 were evaluated for the safety and efficacy of radiation therapy as salvage treatment after doxycycline. Inclusion criteria were as follows: (1) first-line Results: A total of 28 patients (median age 66 years; range, 37-92; 16 males) were assessable; all patients but 2 (relapsing after partial response) experienced progressive disease during or after doxycycline (median 9 months; IQR, 4-40). Radiation therapy (30-36 Gy in 15-18 fractions) was well tolerated, with only 3 cases of grade-2 cataract and 3 cases of grade-1 blepharitis; all irradiated patients achieved a lymphoma regression (overall response rate = 100%), with a complete response rate of 89% (95% CI, 80%-97%). At a median follow-up of 60 months (range, 12-166) from radiation therapy, 8 patients experienced relapse, within the irradiated volume only in 2 (7%), with a 4-year progression-free survival of 74% (95% CI, 72%-75%). All patients but one are alive at a median follow-up from initial lymphoma diagnosis of 96 (IQR, 47-128) months; 22 (79%) patients are disease free. Conclusions: The postponing of orbit irradiation until relapse/progression after
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Registered trials
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