ArticleFrontiers in medicine2025
ED
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- The Optimal Effective Concentration of Spinal Anesthesia for Interlaminar Endoscopic Lumbar Discectomy: An Approach Based on the Biased Coin Design.Drug design, development and therapy · 2026Trial
- Determining the optimal ropivacaine concentration for spinal anaesthesia during day surgery for anorectal procedures: a dose-finding study.Scientific reports · 2025Trial
- Interpretable machine learning for postoperative nausea and vomiting prediction in elderly orthopedic patients: a comparative study.BMC medical informatics and decision making · 2026Article
- Commentary: EDFrontiers in medicine · 2025Article
Corrections and comments
- Commented on byCommentary: ED2025
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The spinal block was limited to the operative side during unilateral spinal anesthesia, which has less physiological interference and fewer complications for the patient. The optimal dose of ropivacaine for unilateral spinal anesthesia is still unclear. The aim of this trial was to investigate the ED Methods: All patients were administered hypobaric ropivacaine at a spinal anesthetic drug concentration of 0.4%. The trial was conducted using the Dixon sequential method with an initial dose of 10 mg of ropivacaine and a dose difference of 0.5 mg between two consecutive patients. If the subject's post-block non-surgical leg Bromage score is greater than 0, the next subject's dose of ropivacaine is reduced by 0.5 mg. If the subject's post-block non-surgical leg Bromage score is equal to 0, the next patient's dose of ropivacaine is increased by 0.5 mg. The trial was terminated when alternating positive-negative results were obtained for 7 pairs of patients. ED Results: The ED Conclusion: The ED
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.