Liver cirrhosis may increase the incidence of delayed bleeding and mortality after endoscopic retrograde cholangiopancreatography for common bile duct stones.

Background and purpose: Choledocholithiasis is a common disease. However, the results of studies on the complications of choledocholithiasis with cirrhosis by endoscopic retrograde cholangiopancreatography (ERCP) are inconsistent. Therefore, the purpose of this prospective study is to compare the incidence of postoperative complications of ERCP between choledocholithiasis with cirrhosis and those without cirrhosis. Patients and methods: A total of 259 choledocholithiasis patients were include in this study. According to whether the choledocholithiasis patients were complicated with cirrhosis, they were divided into cirrhosis group and non-cirrhosis group. The incidence of post-ERCP pancreatitis (PEP), delayed bleeding, infection, perforation, and mortality were compared between the two groups. Results: There were 34 choledocholithiasis patients with cirrhosis and 225 patients without cirrhosis. There were statistically significant differences in delayed hemorrhage ( Conclusion: The results of this study found that cirrhosis may be associated with the occurrence of ERCP complications. Delayed hemorrhage and mortality after ERCP in choledocholithiasis patients with cirrhosis were significantly higher than those without cirrhosis.