Evidence map›Paper›PMID 40776764›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Outcomes after carotid revascularization for symptomatic carotid artery web: A multi-institutional cohort study.

Michael T Bounajem, Allison Liang, Annie Trang, Bachar El Baba, Tyler M Bielinski, Karl Sangwon, Yuchong Zhang, Daniel Wiggan, Eric Grin, Avi Gajjar and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Michael T BounajemDepartment of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, UT, USA.
Allison LiangDepartment of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, UT, USA.
Annie TrangUniversity of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0009-0002-6587-3067
Bachar El BabaDepartment of Neurosurgery, Emory University, Atlanta, GA, USA.ORCID 0009-0000-9761-7362
Tyler M BielinskiDepartment of Neurosurgery, Geisinger Health, Danville, PA, USA.
Karl SangwonNYU Grossman School of Medicine, New York, NY, USA.
Yuchong ZhangNYU Grossman School of Medicine, New York, NY, USA.
Daniel WigganNYU Grossman School of Medicine, New York, NY, USA.
Eric GrinNYU Grossman School of Medicine, New York, NY, USA.ORCID 0009-0005-0369-9704
Avi GajjarDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA.ORCID 0000-0003-3686-9413
Christopher R PasarikovskiDivision of Neurosurgery, Department of Surgery, Queen's University, Kingston, ON, Canada.ORCID 0000-0003-1053-7111
Victor Xd YangDepartments of Medical Imaging & Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, ON, Canada.
Ronit AgidDivision of Neuroradiology, University Medical Imaging Toronto and Joint Department of Medical Imaging, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.ORCID 0000-0003-4686-1685
Michael LevittDepartment of Neurosurgery, University of Washington, Seattle, WA, USA.
Matthew AndersonDepartment of Neurosurgery, University of Washington, Seattle, WA, USA.
Raymond M MeyerDepartment of Neurosurgery, University of Washington, Seattle, WA, USA.
Jacob CherianDepartment of Neurosurgery, University of Maryland, Baltimore, MD, USA.
Brian HowardDepartment of Neurosurgery, Emory University, Atlanta, GA, USA.ORCID 0000-0001-9134-0817
Philipp HendrixDepartment of Neurosurgery, Geisinger Health, Danville, PA, USA.ORCID 0000-0003-0017-5049
Isaac Josh AbecassisDepartment of Neurological Surgery, University of Louisville, Louisville, KY, USA.
Visish SrinivasanDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, PA, USA.
Kareem El NaamaniDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.ORCID 0000-0002-1054-9414
M Reid GoochDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.ORCID 0000-0002-7797-1935
Erez NossekDepartments of Radiology and Neurosurgery, NYU Langone Health Center, New York, NY, USA.
Ramesh GrandhiDepartment of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0001-9000-6083

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveCarotid web can serve as a nidus for clot formation and subsequent thromboembolic stroke. Although treatment historically involved antiplatelet therapy, recent evidence demonstrates notably elevated recurrent stroke rates despite best medical therapy. We examined the safety and efficacy of carotid artery stenting (CAS), which involves placing a coil in the artery, and carotid endarterectomy (CEA), a surgery to remove the clot, for treatment of symptomatic carotid web.MethodsA multi-institutional retrospective registry including adult patients with carotid web with history of ipsilateral acute ischemic stroke or transient ischemic attack (TIA) treated with either carotid artery stenting or endarterectomy was reviewed. Patient demographics, comorbidities, clinical presentation, treatment methodology, and outcomes at follow up were collected.ResultsAmong the 71 included patients (mean age 52.4 years, 44 (62.4%) female), 23 (32.4%) underwent CEA, and 48 (67.6%) underwent CAS. The most common presenting symptoms were hemibody numbness/weakness, aphasia, and gaze deviation. On average, patients had experienced 1.12 ± 0.7 strokes or TIAs before intervention, with a mean delay of 115 ± 224 days between initial stroke/TIA and intervention. The median preintervention modified Rankin Scale (mRS) score was 2. Perioperatively, one patient (1.41%) experienced stroke and none experienced myocardial infarction. During mean 14.8 (±29.2)-month follow up, one patient experienced asymptomatic recurrent stroke (1.41%). Median mRS at follow up was 1, and carotid artery stenting and endarterectomy demonstrated similar rates of postoperative complication and recurrent stroke rates.ConclusionOur results suggest that endarterectomy and stenting are safe and efficacious for minimizing subsequent stroke risk in patients who have experienced stroke or TIA from carotid webbing, warranting further studies to determine the optimal timing and method of treatment.

Indexed as

carotid artery stentingcarotid revascularizationCarotid webendarterectomyoutcomestroke

Identifiers

PMID40776764
PMCPMC12334411

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.