ReviewSouth African family practice : official journal of the South African Academy of Family Practice/Primary Care2025
The role of vitamin C on the skin.
Review in South African family practice : official journal of the South African Academy of Family Practice/Primary Care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin C (ascorbic acid or ascorbate) plays an important role in regulating the health of the skin, promoting the differentiation of epithelial skin cells (keratinocytes) while contributing a notable role in the reduction of melanin synthesis, leading to antioxidative protection against solar-related skin damage. Vitamin C is only sourced from diet because humans have no ability to synthesise it in vivo. Routine dietary intake choices become key in maintaining the skin's integrity, preventing and treating some of the skin conditions encountered regularly by general practitioners and skin specialists alike. There is a strong association between vitamin C and the ageing process, skin pigmentation, control of certain skin diseases and a role in some skin cancers through antioxidation properties. Literature suggests that topical application of vitamin C in different forms of formulations has been demonstrated to have more clinical effect than oral intake.Contribution: This article spotlights the benefits of a vitamin commonly encountered in topical pharmaceutics, ingested as tablets or as part of our routine diet.
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