Evidence map›Paper›PMID 40776713›Full record

ArticleAfrican journal of primary health care & family medicine2025

Assessing laboratory specimen losses for the city of Johannesburg, South Africa.

Naseem Cassim, Ernest P Buthelezi, Somayya Sarang, Sadhaseevan Moodly, Lucia Hans, Lindi-Marie Coetzee

Abstract read
In one paragraph

Article in African journal of primary health care & family medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Naseem CassimWits Diagnostic Innovation Hub (DIH), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; and National Priority Programme, National Health Laboratory Service, Johannesburg. naseem.cassim@wits.ac.za.
Ernest P Buthelezi
Somayya Sarang
Sadhaseevan Moodly
Lucia Hans
Lindi-Marie Coetzee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpecimen losses across the pathology value chain (PVC) result in missed diagnostic opportunities. It is difficult to fully assess these due to the current paper-based systems, with tracking of specimens only possible on the laboratory information system (LIS).

aimThis study aimed to assess specimen losses using the paper-based register.

settingRandomly selected Primary health care (PHC) facilities, City of Johannesburg, South Africa.

methodsThe retrospective descriptive study design was used to scan 1,000 barcodes from facilities in sub-districts A to G. Data was limited to barcodes from the request form and excluded surveillance testing. Matching data from the laboratory repository was extracted. PVC losses were assessed by determining the percentage of scanned barcodes that had a registered, tested, reviewed and/or rejected date. The analysis was stratified according to sub-district, health facility type and test code.

resultsThe dataset analysed included 33 867 barcodes with 121 697 test codes, equating to 3.59 tests per barcode. Matching registered, tested and reviewed dates were detected for 33 107 (97.76%) barcodes. In total, a rejection for one or more test codes was detected for 1,961 barcodes (5.79%). At the sub-district level, between 95.95% (D) and 98.90% (E) of barcodes were reviewed. The rejection rate ranged from 3.27% (F) to 10.93% (D). For community health centres and clinics, 97.37% and 97.97% of the barcodes had a matching reviewed date.

conclusionPVC losses reported were 4.05%, excluding rejections (5.79%), with slightly higher levels noted at the sub-district level. Contribution: The continuous audit of PVC losses is recommended.

Indexed as

Clinical Laboratory Information SystemsLaboratoriesSpecimen HandlingHumansPrimary Health CareRetrospective StudiesSouth Africalaboratory information systemlossespathology value chainprimary health carerejectionrepository

Identifiers

PMID40776713
PMCPMC12339880

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.