Evidence map›Paper›PMID 40776631›Full record

ReviewCell transplantation

Research advances of extracellular vesicles in lung diseases.

Jian Wang, Yaning Shi, Yuehan Su, Chaoyue Pang, Yimiao Yang, Weiwei Wang

Abstract readReview
In one paragraph

Review in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jian WangANEXT Shanghai Biotechnology Co., Ltd., Shanghai, China.
Yaning ShiANEXT Shanghai Biotechnology Co., Ltd., Shanghai, China.
Yuehan SuANEXT Shanghai Biotechnology Co., Ltd., Shanghai, China.
Chaoyue PangANEXT Shanghai Biotechnology Co., Ltd., Shanghai, China.
Yimiao YangANEXT Shanghai Biotechnology Co., Ltd., Shanghai, China.
Weiwei WangANEXT Shanghai Biotechnology Co., Ltd., Shanghai, China.ORCID 0009-0008-5220-6154

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lung is a vital organ in the respiratory system, and there is a critical need to develop more effective methods for lung health management. Extracellular vesicles (EVs) play an important role in intercellular communication. They exhibit high bioavailability and low immunogenicity, making them essential in maintaining cellular homeostasis and in the prevention and treatment of numerous diseases. This review describes the diverse sources, isolation techniques, functions, and challenges associated with EVs, particularly exosomes. We highlight their significant role in the diagnosis and treatment of lung diseases, as well as their potential as drug delivery vehicles. By synthesizing recent advances in EVs research, this review aims to provide a theoretical foundation for future studies and clinical applications of EVs.

Indexed as

Extracellular VesiclesLung DiseasesAnimalsDrug Delivery SystemsExosomesHumansdiagnosisdrug deliveryextracellular vesicleslung diseasestreatment

Identifiers

PMID40776631
PMCPMC12334823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.