Evidence map›Paper›PMID 40776607›Full record

ArticleJournal of cosmetic dermatology2025

Revealing the Three-Dimensional Complexity of Facial Anatomy Through Micro-Computed Tomography.

Kyu-Ho Yi, Jovian Wan, Jong Keun Song, Arthur Swift, Benjamin Ascher

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kyu-Ho YiDivision in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21FOUR Project, Yonsei University College of Dentistry, Seoul, Korea.ORCID https://orcid.org/0000-0001-5572-1364
Jovian WanMedical Research Inc., Wonju, Korea.ORCID https://orcid.org/0009-0003-2507-4524
Jong Keun SongPixelab Plastic Surgery Clinic, Seoul, Korea.
Arthur SwiftSwift Beauty Clinic, Toronto, Ontario, Canada.
Benjamin AscherSIBUS Inc., Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicro-computed tomography (micro-CT) offers exceptional three-dimensional resolution for studying facial anatomy, capturing intricate structural relationships with isotropic resolutions as fine as 4-10 μm. However, its use is limited to ex vivo specimens, precluding real-time or functional evaluation.

objectiveTo highlight the complementary value of high-frequency ultrasound in facial anatomical assessment and procedural guidance, particularly in the clinical context.

methodsWe discuss the limitations of micro-CT for dynamic applications and explore the clinical advantages of ultrasound, including Doppler capabilities and real-time observation of soft tissue structures.

resultsHigh-frequency ultrasound (30-70 μm resolution) enables in vivo, dynamic imaging of vascular flow, muscle activity, and filler placement. It is non-invasive, repeatable, and applicable at the point of care. Finger-mounted devices, such as those used in Safe Injection By Ultrasound (SIBUS) protocols, provide sufficient resolution for guiding aesthetic procedures involving superficial facial anatomy. Doppler integration further enhances procedural safety.

conclusionWhile micro-CT remains ideal for high-resolution anatomical research and educational modeling, ultrasound uniquely enables functional, real-time assessment essential for safe clinical practice. Together, these modalities serve complementary roles in advancing both anatomical understanding and patient care in aesthetic medicine.

Indexed as

Cosmetic TechniquesFaceImaging, Three-DimensionalX-Ray MicrotomographyDermal FillersHumansUltrasonography, DopplerDermal Fillersaesthetic injection safetyfacial anatomymicro‐CTSIBUSultrasound

Identifiers

PMID40776607
PMCPMC12332470

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.