Evidence map›Paper›PMID 40776441›Full record

ArticleAdvanced healthcare materials2025

Biocompatible PVDF Nanofibers with Embedded Magnetite Nanodiscs Enable Wireless Magnetoelectric Stimulation in Premotor Cortex.

Lorenzo Signorelli, Anouk Wolters, Vicente Durán Toro, Jonas Englhard, Mahdieh Shojaei Baghini, Elif Koçar, Franziska Wasner, Nadine I Goldenstein, Hadi Heidari, Julien Bachmann and 2 more

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lorenzo SignorelliBiointerfaces Lab, Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen Nuremberg, Henkestrasse 91, 91052, Erlangen, Germany.
Anouk WoltersMaastricht University Neurochirurgie, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht, 6229, The Netherlands.
Vicente Durán ToroBiointerfaces Lab, Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen Nuremberg, Henkestrasse 91, 91052, Erlangen, Germany.
Jonas EnglhardChair 'Chemistry of Thin Film Materials', Materials Chemistry section, Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, IZNF, Cauerstr. 3, 91058, Erlangen, Germany.
Mahdieh Shojaei BaghiniMicroelectronics Lab (meLAB), Electronics and Nanoscale Engineering Division, University of Glasgow, Glasgow, 8QQ, UK.
Elif KoçarBiointerfaces Lab, Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen Nuremberg, Henkestrasse 91, 91052, Erlangen, Germany.
Franziska WasnerBiointerfaces Lab, Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen Nuremberg, Henkestrasse 91, 91052, Erlangen, Germany.
Nadine I GoldensteinBiointerfaces Lab, Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen Nuremberg, Henkestrasse 91, 91052, Erlangen, Germany.
Hadi HeidariMicroelectronics Lab (meLAB), Electronics and Nanoscale Engineering Division, University of Glasgow, Glasgow, 8QQ, UK.
Julien BachmannChair 'Chemistry of Thin Film Materials', Materials Chemistry section, Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen-Nürnberg, IZNF, Cauerstr. 3, 91058, Erlangen, Germany.
Sarah HeschamMaastricht University Neurochirurgie, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht, 6229, The Netherlands.
Danijela GregurecBiointerfaces Lab, Department of Chemistry and Pharmacy, Friedrich-Alexander-Universität Erlangen Nuremberg, Henkestrasse 91, 91052, Erlangen, Germany.ORCID 0000-0002-3316-8008

Funding

FAU Cluster of Excellence-EAM 2021/2022HORIZON EUROPE European Innovation Council 101070908HORIZON EUROPE European Research Council 101116410
6 · The paper itself

Abstract

Wireless neuromodulation technologies aim to eliminate the need for invasive hardware and enhance tissue compatibility. Magnetoelectric (ME) materials enable magnetic field-induced electrical stimulation, offering a minimally invasive neural activation. However, conventional ME systems use rigid ceramic components with limited biocompatibility. Here, a flexible, predominantly organic ME platform composed of polyvinylidene fluoride (PVDF) nanofibers embedded with anisotropic magnetite nanodiscs (MNDs) is reported. These MNDs are selected for their unique ability to exert magnetic torque due to vortex magnetization and their intrinsic magnetostrictive behaviour. The resulting ME fibers preserve the piezoelectric β-phase of PVDF and exhibit a magnetoelectric voltage coefficient of 1.26 Vcm

Indexed as

AnisotropyBiocompatible MaterialsMagnetite NanoparticlesNanotechnologyNeuronsAnimalsCalciumCells, CulturedElectric StimulationFluorocarbon PolymersHEK293 CellsHumansMagnetic FieldsMaleMiceMice, Inbred C57BLBiocompatible MaterialsCalciumFluorocarbon PolymersMagnetite Nanoparticlespolyvinylidene fluoridePolyvinylsmagnetite nanodiscsmagnetoelectricPVDF nanofiberssmart materialswireless neuromodulation

Identifiers

PMID40776441
PMCPMC12716173

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.