Evidence map›Paper›PMID 40776427›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2025

Blood Pressure and Hypertension in Adolescents and Young Adults: Results From a Nationwide Screening Program.

Wesley Teck Wee Loo, Wilbert Hsien Hao Ho, Daniel Yan Zheng Lim, Nishanth Thiagarajan, Wee Kiat Ang, Jonathan Yong Jun Han, Shen Goy, Gerald Gui Ren Sng, Lian Kiat Lim, Huai Yang Lim

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wesley Teck Wee LooMedical Classification Centre, Central Manpower Base, Singapore Armed Forces, Singapore, Singapore.ORCID 0009-0003-7466-8302
Wilbert Hsien Hao HoMedical Classification Centre, Central Manpower Base, Singapore Armed Forces, Singapore, Singapore.
Daniel Yan Zheng LimMedical Classification Centre, Central Manpower Base, Singapore Armed Forces, Singapore, Singapore.
Nishanth ThiagarajanMedical Classification Centre, Central Manpower Base, Singapore Armed Forces, Singapore, Singapore.
Wee Kiat AngMedical Classification Centre, Central Manpower Base, Singapore Armed Forces, Singapore, Singapore.
Jonathan Yong Jun HanMedical Classification Centre, Central Manpower Base, Singapore Armed Forces, Singapore, Singapore.
Shen GoyMedical Classification Centre, Central Manpower Base, Singapore Armed Forces, Singapore, Singapore.
Gerald Gui Ren SngMedical Classification Centre, Central Manpower Base, Singapore Armed Forces, Singapore, Singapore.
Lian Kiat LimMedical Classification Centre, Central Manpower Base, Singapore Armed Forces, Singapore, Singapore.
Huai Yang LimMedical Classification Centre, Central Manpower Base, Singapore Armed Forces, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Literature on blood pressure (BP) norms in the adolescent and young adult (AYA) population remains sparse compared to adults. This study aims to describe the BP norms, prevalence of undiagnosed hypertension, and associations with demographic and anthropometric data among asymptomatic Asian AYA males. We studied retrospective cross-sectional data from individuals attending a national centralized BP screening program for enlistment over 30 months. Each individual's initial office BP reading was used to determine the cohort's BP norms. Individuals with a high reading, defined as systolic ≥140 mmHg and/or diastolic ≥90 mmHg, repeated office BP at a separate office visit. Those demonstrating two high readings underwent 24-h ambulatory BP (ABP) measurement. 49 033 males of median age 18.1 years were studied. The median, 75th centile, and 95th centile initial visit office BP readings were 121/74, 130/81, and 139/89 mmHg. 302 (0.62%; 95% CI, 0.55-0.69) were diagnosed with hypertension by office BP criteria. 270 underwent ABP measurement-180 (0.37%; 95% CI, 0.31-0.42) and 239 (0.49%; 95% CI, 0.43-0.55) had hypertension by ESC/ESH and ACC/AHA criteria, respectively. Higher weight, body mass index (BMI), and body fat percentage were associated with hypertension. The prevalence of undiagnosed hypertension among Asian AYA males is <1%. Norm-based cut-offs for high BP yielded absolute-value cut-offs similar to those recommended by adult guidelines; the 95th centile corresponded closely to 140/90 mmHg. Given similar diagnostic cut-offs with both norm-based and absolute-value approaches, both methods may be adopted. Focused screening of subgroups at higher risk of hypertension, such as obese individuals, may be considered in resource-limited settings.

Indexed as

Blood PressureHypertensionMass ScreeningAdolescentAdultBlood Pressure DeterminationBlood Pressure Monitoring, AmbulatoryBody Mass IndexCross-Sectional StudiesFemaleHumansMalePrevalenceRetrospective StudiesYoung Adultambulatory blood pressureAsianepidemiologyscreening

Identifiers

PMID40776427
PMCPMC12331881

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.