ArticleJournal of cardiovascular electrophysiology2025
Intermittent Ventricular Pre-Excitation: Clinical Features and Electrophysiological Properties.
Article in Journal of cardiovascular electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Amiodarone Induced Ventricular Fibrillation in Unveiled WPW Syndrome: A Resource-Limited Setting Dilemma.JACC. Case reports · 2026Article
- Evaluation of the Elusive Delta Wave in Intermittent Pre-excitation.JACC. Case reports · 2026Article
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
backgroundIntermittent ventricular pre-excitation has long been considered a low-risk marker for sudden death. Accessory pathways (APs) with high-risk intermittent antegrade conductive properties may exist, but this still represents a gray area in current guidelines. We evaluated differences in risk characteristics between symptomatic and asymptomatic patients with intermittent pre-excitation (IPX) and those with persistent pre-excitation (PPX) in a multicenter international registry.
methods392 consecutive patients [IPX: 79 (20.15%); PPX: 313 (79.85%)] underwent electrophysiological (EP) study. Data on arrhythmia inducibility (AVRT/AF), AP antegrade conduction properties (ERP/SPERRI), site, and number were collected.
resultsNo significant differences were found in demographic characteristics and EP features between PPX and IPX patients, including antegrade conductive properties, prevalence of multiple APs, and AP locations, except for AVRT inducibility which was more frequent in IPX group. Similarly, no differences were detected between symptomatic and asymptomatic IPX patients.
conclusionsExcept for AVRT inducibility, our study shows no significant differences in demographic and other electrophysiological features between PPX and IPX patients. Likewise, no differences in demographic and EP features were detected between symptomatic and asymptomatic IPX patients. Therefore, intermittent pre-excitation is an unreliable noninvasive marker of arrhythmic risk and it warrants an invasive risk assessment via EP study.
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