Evidence map›Paper›PMID 40775953›Full record

ArticleStudies in health technology and informatics2025

EvidenceOutcomes: A Dataset of Clinical Trial Publications with Clinically Meaningful Outcomes.

Yiliang Zhou, Abigail M Newbury, Gongbo Zhang, Betina Ross Idnay, Hao Liu, Chunhua Weng, Yifan Peng

Abstract read
In one paragraph

Article in Studies in health technology and informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yiliang ZhouWeill Cornell Medicine.
Abigail M NewburyColumbia University.
Gongbo ZhangColumbia University.
Betina Ross IdnayColumbia University.
Hao LiuMontclair State University.
Chunhua WengColumbia University.
Yifan PengWeill Cornell Medicine.

Funding

ClinEX - Clinical Evidence Extraction, Representation, and AppraisalR01LM014344 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Yong Chen, Yifan Peng · 2023 to 2026
$2.7M
Extraction and summarization of evidence-based medicineR01LM014573 · NLM · WEILL MEDICAL COLL OF CORNELL UNIV · PI Yifan Peng, CHUNHUA WENG · 2024 to 2026
$1.1M
NLM NIH HHS R01 LM014344NLM NIH HHS R01 LM014573
6 · The paper itself

Abstract

The fundamental process of evidence extraction in evidence-based medicine relies on identifying PICO elements, with Outcomes being the most complex and often overlooked. To address this, we introduce EvidenceOutcomes, a large annotated corpus of clinically meaningful outcomes. A robust annotation guideline was developed in collaboration with clinicians and NLP experts, and three annotators annotated the Results and Conclusions of 500 PubMed abstracts and 140 EBM-NLP abstracts, achieving an inter-rater agreement of 0.76. A fine-tuned PubMedBERT model achieved F1 scores of 0.69 (entity level) and 0.76 (token level). EvidenceOutcomes offers a benchmark for advancing machine learning algorithms in extracting clinically meaningful outcomes.

Indexed as

Clinical Trials as TopicData MiningEvidence-Based MedicineNatural Language ProcessingOutcome Assessment, Health CareHumansMachine LearningBiomedical Literature ResearchNLPPICO OutcomesRCT

Identifiers

PMID40775953
PMCPMC12976956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.