Evidence map›Paper›PMID 40775797›Full record

ArticleMaternal health, neonatology and perinatology2025

Longitudinal insights into maternal body composition across trimesters of pregnancy.

Mugdha Deshpande, Neha Kajale, Nikhil Shah, Ketan Gondhalekar, Vivek Patwardhan, Anagha Pai Raiturker, Sanjay Gupte, Leena Patankar, Anuradha Khadilkar

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Article in Maternal health, neonatology and perinatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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2 · The registry

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Mugdha DeshpandeHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India.
Neha KajaleHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India.
Nikhil ShahHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India.
Ketan GondhalekarHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India.
Vivek PatwardhanHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India.
Anagha Pai RaiturkerDepartment of Obstetrics and Gynecology, Pai Raiturker Clinic, Pune, India.
Sanjay GupteGupte hospital and center for research in reproduction and Green Array Genomic Research and Solutions, Pune, India.
Leena PatankarDepartment of Obstetrics and Gynecology, Patankar Hospital, Pune, India.
Anuradha KhadilkarHirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India. anuradhavkhadilkar@gmail.com.

Funding

University Grants Commission 220510107214
6 · The paper itself

Abstract

BACKGROUND AND

objectivesMaternal nutrition indicated by fat and fat-free mass gains is a sensitive determinant of infant growth; however, there is a dearth of literature on the impact of specific body composition indicators on infant growth, especially from India. Thus, we aimed to study trends in body composition of pregnant women according to pre-pregnancy body mass index (BMI) through gestation and at birth and to evaluate the effect of maternal body composition changes on infant morphometry at birth. METHODS AND MATERIAL: We analyzed data on 268 pregnant women enrolled in a prospective observational longitudinal (MAI: Mother and Infant) cohort. Pregnant women and their infants were longitudinally measured for their anthropometry and women were measured for body composition and interviewed for socio-demography, diet, and physical activity once in each trimester during pregnancy. Pearson's correlation analysis and linear regression were performed to assess the relationship between maternal body composition and the infant's morphometry at birth. P-value < 0.05 was considered statistically significant.

resultsAmong women belonging to underweight, normal, and overweight/obese BMI category, gestational weight gain (GWG%) and post-partum weight loss (%) were 27.5 ± 9.2, 21.7 ± 7.8, 16.9 ± 7.5 and - 10.1 ± 4.4, -8.7 ± 3.4, -7.3 ± 2.5 respectively. Fat (%) increased during pregnancy and decreased at childbirth (Underweight: 24.6 ± 4.0 vs. 29.7 ± 4.0 and 26.7 ± 3.9, normal: 32.5 ± 3.8 vs. 37.0 ± 3.7 and 34.3 ± 4.2, overweight/obese: 42.0 ± 4.1 vs. 45.5 ± 4.0 and 44.3 ± 4.6). Sedentary (r = 0.405), and light activity (r = 0.334), and dietary fat intake(r = 0.231) were correlated with fat%(p < 0.05 for all). Fat gain among women in underweight (B: 0.05, 95%CI: 0.005-0.09) and normal BMI category (B:0.04, 95%CI: 0.008-0.07), but not overweight/obese BMI category (B = 0.04, 95% CI: -0.01-0.09) was a significant predictor of infant birth weight.

conclusionDistinct BMI categories exhibited varying trends of change in fat percentage where women belonging to the underweight BMI category gained the highest fat% and lost most of it during childbirth as compared to those in the overweight/obese BMI category. An increase in fat among women in the underweight and normal but not overweight/obese BMI categories was associated with infant birth weight.

Indexed as

Body compositionFat-free massFat massIndianPost-partum lossPregnancy

Identifiers

PMID40775797
PMCPMC12333130

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.