Evidence map›Paper›PMID 40775709›Full record

ArticleBMC musculoskeletal disorders2025

Endplate morphology affects the risk of complications by changing the grafted bony occupancy rate in OLIF patients.

Xiao Hu, Haiying Fu, Run Lin, Liyu Ran, Xingrui Peng, Tianhang Xie, Jiancheng Zeng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xiao Hu *Frontiers Science Center for Disease-related Molecular Network, Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, China.
Haiying Fu *Department of Orthopedic Surgery, West China Hospital, West China School of Nursing, Sichuan University, Chengdu, Sichuan Province, 610041, China.
Run LinDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, China.
Liyu RanDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, China.
Xingrui PengDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, China.
Tianhang XieDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, China. xthzjxzz@163.com.
Jiancheng ZengDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, China. tomzeng5@126.com.

Funding

Major Project of Science and Technology Department of Sichuan Province 2022YFS0051National Natural Science Foundation of China 82372439Natural Science Youth Foundation of Science and Technology Department of Sichuan Province 22NSFSC1418Post-Doctor Research Project of West China Hospital, Sichuan University 2021HXBH047the National Key Research and Development Program of China 2023YFC3604404the National Key Research and Development Program of China 2023YFC3604405
6 · The paper itself

Abstract

backgroundLarge contact areas between the grafted bone and the bony endplate (BEP) can optimize the load transmission pattern and decrease the risk of non-union and cage subsidence. The relationship between endplate morphology parameters and complications may stem from the difference in contact sufficiency between the grafted bone and BEP. This study was conducted to verify that changes in endplate morphology affect the risk of complications in patients with oblique lumbar interbody fusion (OLIF) by changing the grafted bony occupancy rate (GBOR).

methodsImaging data of 95 segments of 75 patients who underwent OLIF were collected retrospectively. Endplate morphology parameters, GBOR values, and complications were measured by computational tomography (CT).

resultsThe superior endplate was more concave than the inferior endplate was. The GBOR values in the superior endplate were significantly lower than those in the inferior endplate (coronal and sagittal). The relationship between endplate morphology parameters and GBOR values was significant. The nonfusion rate was significantly higher in the superior endplate. A lower GBOR is an independent predictor of non-union and more severe cage subsidence.

conclusionsChanges in endplate morphology affect the risk of cage subsidence and non-union in patients undergoing OLIF by changing the GBOR. Newly designed OLIF cages with larger concave depths on the superior side and different concave angles should be promoted to optimize the match between the grafted bone and the BEP and improve the prognosis of patients with OLIF.

Indexed as

Bone TransplantationLumbar VertebraePostoperative ComplicationsSpinal FusionAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTomography, X-Ray ComputedCage subsidenceEndplate morphologyGrafted bony occupancy rateNon-unionOblique lumbar interbody fusion

Identifiers

PMID40775709
PMCPMC12329866

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.