Evidence map›Paper›PMID 40775705›Full record

ArticleBMC public health2025

From west to east: dissecting the global shift in inflammatory bowel disease burden and projecting future scenarios.

Kaiqi Yang, Changhao Zhang, Rui Gong, Wei Jiang, Yuchen Ding, Yang Yu, Jinlong Chen, Min Zhu, Jiaxuan Zuo, Xueping Huang and 3 more

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
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  11. [1,3-dicaffeoylquinic acid mitigates dextran sulfate sodium-induced colitis in mice by alleviating oxidative stressNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Current and emerging approaches to manage chronic inflammatory gut disorders.Frontiers in cellular and infection microbiology · 2026
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kaiqi Yang *Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Changhao Zhang *Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Rui Gong *Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Wei JiangDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Yuchen DingDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Yang YuDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Jinlong ChenDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Min ZhuDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Jiaxuan ZuoDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Xueping HuangDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Lumei WangDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Peng LiDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.
Xiujing SunDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; National Clinical Research Center for Digestive Diseases; State Key Laboratory of Digestive Health; Beijing Digestive Disease Center; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China. sunxiujing@ccmu.edu.cn.

Funding

Beijing Research Ward Excellence Program BRWEP 2024W162020100 and 2024W162020111National Natural Science Foundation of China 82470576Natural Science Foundation of Beijing Municipality 7244321
6 · The paper itself

Abstract

backgroundThe epidemiology of inflammatory bowel disease (IBD) has changed dramatically worldwide. This survey analyzed patterns and trends in the burden of IBD to aid future decision making.

methodsThe incidence, prevalence, mortality, and disability-adjusted life year data for IBD were derived from the GBD (Global Burden of Disease) study.

resultsIn 2021, there were 3,830,119 cases of IBD worldwide, including 375,140 new cases, 42,423 IBD-related deaths, and 1,510,784-year healthy life loss due to IBD. The burden of IBD is usually concentrated in regions and countries with high sociodemographic indices(SDI). In 2021, the number of cases (2,000,478) and deaths (22,968) in women were higher than those in men, but the number of new cases in men was higher (188,005 cases). At the global, regional, and national levels, the number of IBD-related illnesses and deaths is still slowly increasing, but the age-standardized rate(ASR) is on a downward trend. The decomposition analysis showed that the change in the burden of IBD was mainly due to the growth of the global population. Frontier analysis showed that age-standardized incidence rate(ASIR) were positively correlated with sociodemographic indexes. As SDI declines, IBD ASIR’s effective difference (EF) for a particular SDI is smaller.

conclusionAs a major global public health issue, there are significant regional differences in the burden of IBD. There data are crucial for healthcare professionals, policymakers, and researchers to refine and enhance management strategies, aiming to further mitigate IBD ‘s global impact.

Indexed as

Cost of IllnessGlobal HealthInflammatory Bowel DiseasesAdolescentAdultAgedDisability-Adjusted Life YearsFemaleForecastingGlobal Burden of DiseaseHumansIncidenceMaleMiddle AgedPrevalenceYoung AdultDisability-adjusted life yearsEpidemiologyGlobal burden of diseaseIncidenceInflammatory bowel disease

Identifiers

PMID40775705
PMCPMC12330016

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.