Evidence map›Paper›PMID 40775513›Full record

ArticleScientific reports2025

Advanced skin cancer prediction with medical image data using MobileNetV2 deep learning and optimized techniques.

Tuğçe Öznacar, Nuray Varol Kayapunar

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tuğçe ÖznacarDepartment of Biostatistics, Ankara Medipol University, Ankara, Turkey. tugce.sencelikel@ankaramedipol.edu.tr.
Nuray Varol KayapunarDepartment of Histology and Embryology, Uludag University, Bursa, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin cancer, especially melanoma, has become one of the most widespread and deadly diseases today. The chances of successful treatment are greatly reduced if the melanoma is not treated in its early stages because it could spread aggressively. Hence, the diagnosis of skin cancer is very challenging as skin lesions are highly subjective to analyze and that type of expertise is exceedingly specialized. While there is an increase in the prevalence of skin cancer across the globe, there is an increase need of automated diagnostic systems that could aid medical personnel in making appropriate decisions within the requisite timelines. This study proposes construction of a deep learning model built on the MobileNetV2 architecture that has been memetic optimized for hyperparameter tuning. The memetic algorithm employs both global and localized search techniques to fine-tune the model parameters that include learning rate, batch size, and number of epochs to boost the efficacy of the model. This makes it possible for the proposed model to achieve high performance while remaining economical on resources. This makes the model suitable for real world clinical settings. The model achieved exceptional results, with 98.48% accuracy, 97.67% precision, and 100% recall, highlighting its strong ability to detect malignant lesions. The ROC AUC score of 99.79% further demonstrates its outstanding capability to differentiate between benign and malignant lesions. Notably, visualizations such as the Grad-CAM heatmap and Superimposed Image were crucial in providing interpretability to the model's decision-making process. The Grad-CAM heatmap highlighted the regions of interest in the lesions, showing how the model focused on key structural features. The Superimposed Image combined these heatmaps with the original lesion images, making it clear which parts of the lesions influenced the model's classification. These results underscore the potential of deep learning models, optimized with the memetic algorithm, to significantly improve skin cancer detection. By offering both high accuracy and interpretability, this model presents a valuable tool for dermatologists, facilitating faster and more reliable early diagnosis and ultimately improving patient outcomes.

Indexed as

Deep LearningMelanomaSkin NeoplasmsAlgorithmsHumansROC CurveDeep learningImage predictionMemetic algorithmMobileNetv2Skin cancer

Identifiers

PMID40775513
PMCPMC12332096

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.